Effectiveness of casein phosphopeptide-amorphous calcium phosphate and xylitol chewing gums on salivary pH, buffer capacity, and Streptococcus mutans levels: An interventional study

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dc.contributor.authorPadminee, Krishnanen_US
dc.contributor.authorPoorni, Saravananen_US
dc.contributor.authorDiana, Davidsonen_US
dc.contributor.authorDuraivel, Dasarathanen_US
dc.contributor.authorSrinivasan, Manali Ramakrishnanen_US
dc.date.accessioned2020-01-02T06:45:36Z
dc.date.available2020-01-02T06:45:36Z
dc.date.issued2018-09
dc.description.abstractThe aim of the study is to compare the anticariogenic effectiveness of Casein phosphopeptide- Amorphous Calcium phosphate (CPP-ACP) and xylitol chewing gums based on salivary pH, buffer capacity, and Streptococcus mutans levels. Materials and Methods: A group of twenty individuals in the age group of 18–25 years were randomly divided into two Groups A and B. Test arm A received xylitol gums and test arm B received CPP-ACP gums and they were instructed to use the gums thrice daily for 2 weeks. Unstimulated salivary samples were collected before they began the use of the gums for baseline values, 24 h after beginning the usage of chewing gums and at the end of 14 days. The samples were analyzed for pH, buffer capacity, and S. mutans levels. Results: A statistically significant reduction of salivary S. mutans levels, improvement in salivary pH, and buffer capacity were displayed in both groups 24 h and 14 days after the intervention when compared with baseline. Group B showed more statistically significant improvement in pH than group A after 24 h (P = 0.028) and at the end of 2 weeks (P = 0.041). Conclusion: CPP-ACP has better ability than xylitol in improving the pH of saliva. Both CPP-ACP and xylitol gums individually have remarkable ability in bringing down S. mutans levels while simultaneously improving the pH and buffer of saliva.en_US
dc.identifier.affiliationsDepartment of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, Indiaen_US
dc.identifier.citationPadminee Krishnan, Poorni Saravanan, Diana Davidson, Duraivel Dasarathan, Srinivasan Manali Ramakrishnan. Effectiveness of casein phosphopeptide-amorphous calcium phosphate and xylitol chewing gums on salivary pH, buffer capacity, and Streptococcus mutans levels: An interventional study. Indian Journal of Dental Research. 2018 Sep; 29(5): 616-621en_US
dc.identifier.issn0970-9290
dc.identifier.issn1998-3603
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/192125
dc.languageenen_US
dc.publisherIndian Society for Dental Researchen_US
dc.relation.issuenumber5en_US
dc.relation.volume29en_US
dc.source.urihttps://dx.doi.org/10.4103/ijdr.IJDR_166_17en_US
dc.subjectAnticariogenic efficacyen_US
dc.subjectcasein phosphopeptide - amorphous calcium phosphateen_US
dc.subjectsalivary buffer capacityen_US
dc.subjectsalivary pHen_US
dc.subjectStreptococcus mutansen_US
dc.subjectxylitolen_US
dc.titleEffectiveness of casein phosphopeptide-amorphous calcium phosphate and xylitol chewing gums on salivary pH, buffer capacity, and Streptococcus mutans levels: An interventional studyen_US
dc.typeJournal Articleen_US
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