Detection of rabies virus in different tissues of experimentally infected mice at preclinical and postclinical stages of the disease.

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dc.contributor.authorDutta, M Ken_US
dc.contributor.authorSaha, Ven_US
dc.contributor.authorSarkar, Pen_US
dc.date.accessioned2009-05-28T12:17:59Z
dc.date.available2009-05-28T12:17:59Z
dc.date.issued1992-10-01en_US
dc.description.abstractRabies fixed virus (CVS) was passaged 10 times in mice by intramuscular (im) route followed by experimental inoculation of the titrated virus in 4 groups of mice with the dose of 0.1 ml of 1000 mouse (LD50 0.03 ml) using intracerebral (ic), intravenous (iv), intramuscular (im), intraocular (io), and intranasal (in) routes respectively. No marked variation in clinical signs due to variation of routes could be detected. Involvement of brain with io route could be detected even in preclinical stage. Although the virus could be detected in the postclinical stage in all the tissues under study (brain, skin, salivary gland and corneal impression), with io and ic routes spread of the virus was observed in comparatively higher concentrations.en_US
dc.description.affiliationDepartment of Veterinary Microbiology, Faculty of Veterinary & Animal Sciences, Nadia, India.en_US
dc.identifier.citationDutta MK, Saha V, Sarkar P. Detection of rabies virus in different tissues of experimentally infected mice at preclinical and postclinical stages of the disease. Indian Journal of Experimental Biology. 1992 Oct; 30(10): 877-80en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/57892
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntigens, Viral --analysisen_US
dc.subject.meshBrain --microbiologyen_US
dc.subject.meshCornea --microbiologyen_US
dc.subject.meshMiceen_US
dc.subject.meshRabies --microbiologyen_US
dc.subject.meshRabies virus --immunologyen_US
dc.subject.meshSalivary Glands --microbiologyen_US
dc.subject.meshSkin --microbiologyen_US
dc.titleDetection of rabies virus in different tissues of experimentally infected mice at preclinical and postclinical stages of the disease.en_US
dc.typeJournal Articleen_US
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