Physicochemical Properties and in Vitro Anti-Obesity Potential of Anethum Graveolens (Dill) Seed Cake

Simple item page
dc.contributor.authorAwasthi, A.en_US
dc.contributor.authorBigoniya, P.en_US
dc.contributor.authorGupta, B.en_US
dc.date.accessioned2024-09-24T08:28:04Z
dc.date.available2024-09-24T08:28:04Z
dc.date.issued2024-06
dc.description.abstractThe present study investigates the in vitro anti-obesity potential of Anethum graveolens L. (Family Apiaceae) dill seed cake (DSC). DSC contained dietary fibers, proteins, lignans, and phenolic compounds. Food rich in dietary fiber is vital in lowering dyslipidemia, complications of metabolic disorders, and obesity. DSC was obtained after oil extraction of the dill seed. Physicochemical characterization and lignan profiling were performed by HPLC. An In vitro study assessed the degree of hydrolysis, ?- amylase, ?-glucosidases, and pancreatic lipase inhibitory activity. The DSC has high dietary fiber, moderate protein, and less than ten percent moisture, ash, and fat content with low foreign matter. HPLC chromatogram of DSC showed the presence of lignin-like carvone, perillyl alcohol, perillaldehyde, and cineole. The IC50 value for ?-amylase, ?-glucosidase, and pancreatic lipase inhibitory activity was 60.18 ± 2.21, 456.42 ± 5.32, and 54.13 ± 2.25 µg/ml, respectively. DSC can ameliorate obesity and associated metabolic complications by inhibiting intestinal carbohydrate and fat metabolism and absorption. Study findings provide a basis for developing dill seed as a nutraceutical supplement for obesity management.en_US
dc.identifier.affiliationsSchool of Pharmacy and Research, People’s University, Bhopal, M.P., Indiaen_US
dc.identifier.affiliationsSchool of Life Sciences, University of Westminster, London, W1W6UW, UKen_US
dc.identifier.affiliationsSchool of Pharmacy and Research, People’s University, Bhopal, M.P., Indiaen_US
dc.identifier.citationAwasthi A., Bigoniya P., Gupta B. . Physicochemical Properties and in Vitro Anti-Obesity Potential of Anethum Graveolens (Dill) Seed Cake . International Journal of Pharmaceutical Research and Allied Sciences . 2024 Apr; 13(2): 48-57en_US
dc.identifier.issn2277-3657
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231418
dc.languageenen_US
dc.publisherMeral Publisheren_US
dc.relation.issuenumber2en_US
dc.relation.volume13en_US
dc.source.urihttps://doi.org/10.51847/JGGw7PTBwJen_US
dc.subjectAnethum graveolensen_US
dc.subjectDill seed cakeen_US
dc.subjectLignansen_US
dc.subjectDietary fiberen_US
dc.subjectObesityen_US
dc.titlePhysicochemical Properties and in Vitro Anti-Obesity Potential of Anethum Graveolens (Dill) Seed Cakeen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ijpras2024v13n2p48.pdf
Size:
1.04 MB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Pharmaceutical Research and Allied Sciences