Wound healing profiles of ketorolac, metronidazole and tinidazole administered post-surgically.
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1995-11-01
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Abstract
On dead space wounds, drugs (ketorolac, metronidazole and tinidazole) caused a significant (P < 0.01) decrease in breaking strength, granulation tissue weight and hydroxyproline content in male rats. Both the parameters of excision wound were significantly (P < 0.01) hastened by metronidazole and tinidazole only. Post operative management of wounds with ketorolac (a potent analgesic), metronidazole and tinidazole (for anaerobic infections) may be dealt with the risk of a delay in healing. Both metronidazole and tinidazole promote the epithelization process.
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Prasad D, Rao CM. Wound healing profiles of ketorolac, metronidazole and tinidazole administered post-surgically. Indian Journal of Experimental Biology. 1995 Nov; 33(11): 845-7