Inflammation & apoptosis in spinal cord injury.

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dc.contributor.authorZhang, Ning
dc.contributor.authorYin, Ying
dc.contributor.authorXu, Sheng-Jie
dc.contributor.authorWu, Yong-Ping
dc.contributor.authorChen, Wei-Shan
dc.date.accessioned2012-06-12T09:54:06Z
dc.date.available2012-06-12T09:54:06Z
dc.date.issued2012-03
dc.description.abstractSpinal cord injury (SCI) consists of a two-steps process involving a primary mechanical injury followed by an inflammatory process and apoptosis. Secondary insult is characterized by further destruction of neuronal and glial cells, and leads to expansion of the damage, so that the paralysis can extend to higher segments. With the identification of mechanisms that either promote or prevent neuronal inflammation and apoptosis come new approaches for preventing and treating neurodegenerative disorders. From a clinical perspective, this article discusses novel targets for the development of therapeutic agents that have the potential to protect the spinal cord from irreversible damage and promote functional recovery.en_US
dc.identifier.citationZhang Ning, Yin Ying, Xu Sheng-Jie, Wu Yong-Ping, Chen Wei-Shan. Inflammation & apoptosis in spinal cord injury. Indian Journal of Medical Research. 2012 Mar; 135(3): 287-296.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/138991
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361863/en_US
dc.subjectApoptosisen_US
dc.subjectinflammationen_US
dc.subjectmechanismsen_US
dc.subjectspinal cord injuryen_US
dc.subjecttherapyen_US
dc.subject.meshAnti-Inflammatory Agents --therapeutic use
dc.subject.meshAntioxidants --therapeutic use
dc.subject.meshApoptosis --physiology
dc.subject.meshHumans
dc.subject.meshInflammation --drug therapy
dc.subject.meshInflammation --pathology
dc.subject.meshSpinal Cord Injuries --drug therapy
dc.subject.meshSpinal Cord Injuries --pathology
dc.titleInflammation & apoptosis in spinal cord injury.en_US
dc.typeArticleen_US
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