Metronidazole Induced Reversible Cerebellar Toxicity – a Case Report of Uncommon Side Effects of Commonly Used Drug
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Date
2024-07
Journal Title
Journal ISSN
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Publisher
FORUM: Fraternity of national Research & pUblication Society of Medical sciences
Abstract
Background :Pyogenic liver abscesses carry significant morbidity and mortality and can be difficult to treat, typically requiring drainage and broad-spectrum antibiotics to resolve. Antibiotic regimens will often take several weeks to months after drainage to clear the infection, which can put patients at significant risk for developing serious side effects from long term medication toxicity Metronidazole is a widely used antibiotic against bacteria And protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebella toxicity. History :We present a case of a 56-years male presented with dysarthria, who had positive cerebellar sign . Conclusion The magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for six months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole
Description
Keywords
METRONIDAZOLE, CEREBLLUM, MRI
Citation
Rathwa Shubham, Chauhan Sanket, Thakor Vishal, Pranami Harsh. Metronidazole Induced Reversible Cerebellar Toxicity – a Case Report of Uncommon Side Effects of Commonly Used Drug. Indian Journal of Applied Basic Medical Sciences. 2024 Jul; 26B(2): 1-8