Hydnora africana Derived Phytochemicals against Acetaldehyde Dehydrogenase of Aeromonas hydrophila Causing Septicemia

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dc.contributor.authorTripathy, Debajanien_US
dc.contributor.authorAdhikari, Chandanaen_US
dc.contributor.authorPandey, Mukundjeeen_US
dc.contributor.authorBehera, Bhagyeswarien_US
dc.contributor.authorPradhan, Srimayen_US
dc.contributor.authorSahu, Akshay Kumaren_US
dc.date.accessioned2020-11-18T10:30:10Z
dc.date.available2020-11-18T10:30:10Z
dc.date.issued2020-06
dc.description.abstractFor drug discovery it takes approximately 6 years to expose in the market and for commercial uses. There are different procedure to get success in the drug discovery like preliminary phytochemical analysis, structural elucidation of the bioactive compound, preclinical test and clinical test etc. So to optimize the time for invention of new drug molecule, computer aided drug designing and molecular docking analysis is being used as one of the highly effective methodology. The phytochemical extraction of Hydnora africana plant was reported to inhibit the growth of Aeromonas hydrophilawhich cause Septicemia.“Biovia Discovery Studio” molecular docking methods give us opportunity to identify the effective molecule against the microbes. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” recommended that flavone can effectively deactivate the acetaldehyde dehydrogenase enzyme thereby interrupting the life cycle of the organismen_US
dc.identifier.affiliationsCenturion University of Technology and Management, Odisha, India.en_US
dc.identifier.citationTripathy Debajani, Adhikari Chandana, Pandey Mukundjee, Behera Bhagyeswari, Pradhan Srimay, Sahu Akshay Kumar. Hydnora africana Derived Phytochemicals against Acetaldehyde Dehydrogenase of Aeromonas hydrophila Causing Septicemia. Journal of Pharmaceutical Research International. 2020 Jun; 32(9): 114-117en_US
dc.identifier.issn2456-9119
dc.identifier.issn2231-2919
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215771
dc.languageenen_US
dc.publisherSCIENCEDOMAIN internationalen_US
dc.relation.issuenumber9en_US
dc.relation.volume32en_US
dc.source.urihttps://doi.org/10.9734/JPRI/2020/v32i930539en_US
dc.subjectFlavonen_US
dc.subjectHydnora africanaen_US
dc.subjectAeromonas hydrophilaen_US
dc.subjectSepticemiaen_US
dc.titleHydnora africana Derived Phytochemicals against Acetaldehyde Dehydrogenase of Aeromonas hydrophila Causing Septicemiaen_US
dc.typeJournal Articleen_US
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