The safety and efficacy of oral Arborium plus, a herbal liquid formulation in the treatment of diabetic foot syndrome: an open label study

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dc.contributor.authorChalivendra, Pallavien_US
dc.contributor.authorShaik, Nurul Hameeden_US
dc.contributor.authorBalapalli, Hari Prasaden_US
dc.contributor.authorParasaram, Murali Krishnaen_US
dc.contributor.authorBommadi, Bhavyaen_US
dc.contributor.authorRavanam, Sai Anjanien_US
dc.contributor.authorAttili, Subhaen_US
dc.date.accessioned2020-04-23T08:01:42Z
dc.date.available2020-04-23T08:01:42Z
dc.date.issued2020-04
dc.description.abstractBackground: Diabetic foot ulcers are the most universal cause of non-traumatic amputations of the foot in developing countries. One of the treatment modalities is to improve the peripheral blood supply to the area of ulcer. To this purpose the study was done to evaluate the safety and efficacy of oral Arborium plus (herbal liquid formulation) in the wound closure of diabetic foot patients.Methods: 50 patients were randomly assigned to either of the groups (each group 25 patients) to receive either the test drug (Arborium plus) at tertiary care teaching hospital, it was an open label prospective and interventional parallel group study to evaluate the efficacy and safety of Arborium plus in diabetic foot syndrome. The study participants were randomized into control and intervention groups. Base line measurements of vascular flow was ankle- brachial pressure index (ABPI) and wound size measurement.Results: The baseline characteristics of the patients age in years test and control group 68�.3 and 67�.4 respectively. Male/female in both groups was 21/4 and 22/3 respectively. Duration of diabetes in years 8.65�3 and 8.5�6 respectively. BMI was 25.11�15 and 24.75�85, duration of smoking (years) 17.3�5 and 19.5�.5 respectively in both groups. Among the test group who received the proprietary formulation of Arborium plus, there was a significant reduction in the wound size.Conclusions: Wound healing and ABPI improvements were observed with usage of Arborium plus suggest an improvement in peripheral vascular flow in diabetic foot subjects.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Sri Padmavathi Medical College for Women, Tirupati, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of General Surgery, Sri Padmavathi Medical College for Women, Tirupati, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsSri Padmavathi Medical College for Women, Tirupati, Andhra Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Panchakarma, SV Ayurvedic College and Hospital, Tirupati, Andhra Pradesh, Indiaen_US
dc.identifier.citationChalivendra Pallavi, Shaik Nurul Hameed, Balapalli Hari Prasad, Parasaram Murali Krishna, Bommadi Bhavya, Ravanam Sai Anjani, Attili Subha. The safety and efficacy of oral Arborium plus, a herbal liquid formulation in the treatment of diabetic foot syndrome: an open label study. International Journal of Basic & Clinical Pharmacology. 2020 Apr; 9(4): 528-532en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200592
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2319-2003.ijbcp20201101en_US
dc.subjectOral Arborium plusen_US
dc.subjectDiabetic foot ulceren_US
dc.subjectType-2 diabetesen_US
dc.subjectHerbal formulationen_US
dc.titleThe safety and efficacy of oral Arborium plus, a herbal liquid formulation in the treatment of diabetic foot syndrome: an open label studyen_US
dc.typeJournal Articleen_US
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