Navigating Diagnostic Challenges in Cutaneous Leiomyosarcoma: A Clinical Case Study.

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dc.contributor.authorRaghavan, Ven_US
dc.contributor.authorSithika, ATen_US
dc.contributor.authorChandrasekaran, Ken_US
dc.date.accessioned2024-12-02T11:43:43Z
dc.date.available2024-12-02T11:43:43Z
dc.date.issued2024-07
dc.description.abstractAbstract: Cutaneous Leiomyosarcomas (CL) are rare, constituting just 3% of malignant soft tissue sarcomas. We present a case involving a 40-year-old male with a forearm nodule. Histopathological examination revealed atypical spindle cells with immunohistochemistry confirming Cutaneous Leiomyosarcomas. While the patient had a prior excision for a similar swelling, reports were unavailable. Treatment involved a wide resection with a lesion-free specimen. Cutaneous Leiomyosarcomas commonly presents as a nodular growth in extremities, with a microscopic appearance characterized by spindle-shaped cells exhibiting palisading and atypia. Differential diagnoses include other spindle cell lesions necessitating IHC for confirmation. Recurrence rates underscore the importance of wide excision. Distant metastasis, primarily to the lungs, and identified prognostic factors, such as lesion size and histological grade, contribute to the complex clinical landscape. This case emphasizes the rarity of Cutaneous Leiomyosarcomas, emphasizing the need for thorough diagnostic evaluation and a multidisciplinary approach for effective management.en_US
dc.identifier.affiliationsDepartment of Pathology, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam - 603103, Chengalpattu District, Tamilnadu, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam - 603103, Chengalpattu District, Tamilnadu, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam - 603103, Chengalpattu District, Tamilnadu, Indiaen_US
dc.identifier.citationRaghavan V, Sithika AT, Chandrasekaran K. Navigating Diagnostic Challenges in Cutaneous Leiomyosarcoma: A Clinical Case Study.. Online Journal of Health and Allied Sciences. 2024 Jul; 23(91): 1-2en_US
dc.identifier.issn0972-5997
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/240509
dc.languageenen_US
dc.publisherLight House Polyclinicen_US
dc.relation.issuenumber91en_US
dc.relation.volume23en_US
dc.source.urihttps://www.ojhas.org/issue91/2024-3-11.pdfen_US
dc.subjectCutaneous Leiomyosarcomaen_US
dc.subjectmultidisciplinary approachen_US
dc.titleNavigating Diagnostic Challenges in Cutaneous Leiomyosarcoma: A Clinical Case Study.en_US
dc.typeJournal Articleen_US
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