Navigating Diagnostic Challenges in Cutaneous Leiomyosarcoma: A Clinical Case Study.
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Date
2024-07
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Light House Polyclinic
Abstract
Abstract: Cutaneous Leiomyosarcomas (CL) are rare, constituting just 3% of malignant soft tissue sarcomas. We present a case involving a 40-year-old male with a forearm nodule. Histopathological examination revealed atypical spindle cells with immunohistochemistry confirming Cutaneous Leiomyosarcomas. While the patient had a prior excision for a similar swelling, reports were unavailable. Treatment involved a wide resection with a lesion-free specimen. Cutaneous Leiomyosarcomas commonly presents as a nodular growth in extremities, with a microscopic appearance characterized by spindle-shaped cells exhibiting palisading and atypia. Differential diagnoses include other spindle cell lesions necessitating IHC for confirmation. Recurrence rates underscore the importance of wide excision. Distant metastasis, primarily to the lungs, and identified prognostic factors, such as lesion size and histological grade, contribute to the complex clinical landscape. This case emphasizes the rarity of Cutaneous Leiomyosarcomas, emphasizing the need for thorough diagnostic evaluation and a multidisciplinary approach for effective management.
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Keywords
Cutaneous Leiomyosarcoma, multidisciplinary approach
Citation
Raghavan V, Sithika AT, Chandrasekaran K. Navigating Diagnostic Challenges in Cutaneous Leiomyosarcoma: A Clinical Case Study.. Online Journal of Health and Allied Sciences. 2024 Jul; 23(91): 1-2