Calcium and Phosphorus Metabolism in Patients with Congestive Heart Failure: A Cross-Sectional Study

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dc.contributor.authorChander, Vikasen_US
dc.contributor.authorRPS, Sibiaen_US
dc.contributor.authorMakkar, Gurjeen Kauren_US
dc.contributor.authorSingh, Manjinderen_US
dc.contributor.authorGarg, Parteeken_US
dc.contributor.authorDua, Jasmeen Kauren_US
dc.date.accessioned2024-09-24T08:08:41Z
dc.date.available2024-09-24T08:08:41Z
dc.date.issued2023-04
dc.description.abstractBackground: To study the role of calcium and phosphorus metabolism including the hormones (Vitamin D and PTH) controlling them in patients with congestive heart failure. While extensive studies are available regarding bone mineral metabolism in CKD patient with regard to CVD / HF similar studies in non-CKD patients are sparce, hence the present study. Methods: A cross sectional study was done on a total of 50 patients with signs, symptoms and Echocardiographic findings suggestive of heart failure admitted in medicine wards of Government Medical College Patiala. Patients with type 2 diabetes mellitus, chronic renal disease, thyroid disease and pregnant/lactating mothers were excluded from the study. Serum calcium, phosphorus, Vitamin D and parathyroid hormone were estimated in all patients. Results: The study population consisted of 54% males, 46% females. Mean age was 61.78 +/- 9.18 years. Majority of the patients had cardiac ejection fraction in the range of 22-28%. CAD and HT were present in 58% and 66% patients respectively. Mean values for Vitamin D levels were 19.5 ng/ml. While in patients with normal ejection fraction Vitamin D levels was 29.34ng/ml, it progressively decreased with decreasing ejection fraction, patients with ejection fraction of <20% had Vitamin D levels of 8.98 ng/ml. Similarly mean value of PTH was 89.07 pg/ml and progressively increased with decreasing ejection fraction. Maximum valve of 138.27 pg/ml was found in patients with ejection fraction of <20%. Serum phosphorus value progressively increased with decreasing ejection fraction. Similar trends were found for serum calcium levels also. Conclusion: There is an association between congestive heart failure and calcium and phosphorus metabolism (along with their controlling hormones Vitamin D and parathyroid hormones). Rising levels of phosphorus and PTH and decreasing levels of Vitamin D are directly related with progressive heart failure.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, Indiaen_US
dc.identifier.citationChander Vikas, RPS Sibia, Makkar Gurjeen Kaur, Singh Manjinder, Garg Parteek, Dua Jasmeen Kaur . Calcium and Phosphorus Metabolism in Patients with Congestive Heart Failure: A Cross-Sectional Study. International Journal of Medical Research Professionals. 2023 Mar; 9(2): 25-29en_US
dc.identifier.issn2454-6356
dc.identifier.issn2454-6364
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231035
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume9en_US
dc.source.urihttps://doi.org/10.21276/ijmrp.2023.9.2.006en_US
dc.subjectCalciumen_US
dc.subjectPhosphorusen_US
dc.subjectMetabolismen_US
dc.subjectCongestive Heart Failureen_US
dc.titleCalcium and Phosphorus Metabolism in Patients with Congestive Heart Failure: A Cross-Sectional Studyen_US
dc.typeJournal Articleen_US
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