Epidermal water permeation in vertebrates: an in vitro study using tritiated water.

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dc.contributor.authorPatil, Sen_US
dc.contributor.authorPilo, Ben_US
dc.contributor.authorMenon, Gen_US
dc.date.accessioned2009-05-28T11:04:37Z
dc.date.available2009-05-28T11:04:37Z
dc.date.issued1993-03-01en_US
dc.description.abstractStructural lipids play an important role in the water holding property of the skin. beta emitters are known to pass through the skin barrier. A permeability cell was constructed and tritiated water was used to determine the rate of in vitro water permeation through the epidermis. The epidermal sheets from different classes of vertebrates were compared for water permeation. Some of the samples were treated with solvents, surfactants and conditioners, to fathom permeability changes of the epidermis after these treatments, at various time intervals. Solvent treated epidermal sheets show very high degree of permeation, both in rat pup skin and pigeon skin. Glycerol, Brij 99 and beewax treated skin shows negligible permeation; or rather, helps in retention of water compared to normal and solvent treated skin. Comparison of water permeation in rat, pigeon and lizard skin shows that the reptilian integument is more efficient, as it allows very less permeation of water compared to the avian and mammalian epidermis. These observations suggest that tritiated water could be used for determining in vitro water permeation through the epidermis.en_US
dc.description.affiliationDepartment of Zoology, Faculty of Science, M.S. University of Baroda, India.en_US
dc.identifier.citationPatil S, Pilo B, Menon G. Epidermal water permeation in vertebrates: an in vitro study using tritiated water. Indian Journal of Experimental Biology. 1993 Mar; 31(3): 219-23en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56206
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshColumbidaeen_US
dc.subject.meshEpidermis --metabolismen_US
dc.subject.meshLizardsen_US
dc.subject.meshPermeabilityen_US
dc.subject.meshRatsen_US
dc.subject.meshWater --metabolismen_US
dc.titleEpidermal water permeation in vertebrates: an in vitro study using tritiated water.en_US
dc.typeComparative Studyen_US
dc.typeIn Vitroen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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