Influence of industrial pollutants on thyroid function in Channa punctatus (Bloch).

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dc.contributor.authorBhattacharya, Ten_US
dc.contributor.authorBhattacharya, Sen_US
dc.contributor.authorRay, A Ken_US
dc.contributor.authorDey, Sen_US
dc.date.accessioned2009-05-28T12:57:00Z
dc.date.available2009-05-28T12:57:00Z
dc.date.issued1989-01-01en_US
dc.description.abstractA 30 day exposure of C. punctatus to sublethal levels of phenol, ammonia, mercuric chloride, cadmium chloride and a mixture of the four resulted in an overall activation of guaiacol peroxidase and depression of iodide peroxidase (IPOD) activity and blood T4 titre. Interestingly enough, in case of 15 day ammonia and 1 day mercury exposures, an increase of IPOD activity was accompanied by a decrease in T4 titre. In general, phenol, mercury, cadmium and the mixture of pollutants were found to inhibit LP activity by 56% to 85% while ammonia inhibited lysosomal protease (LP) activity by 70%. Alterations in acid phosphatase (AP) activity indicate changes in the lysosomal membrane characteristics caused by these toxicants. Considering the concomitant alterations in IPOD, T4, LP and AP it is surmised that thyroid function in C. punctatus is influenced by the pollutants by two pathways, one via IPOD pathway affecting T4 synthesis and the other via lysosomal pathway affecting T4 release.en_US
dc.identifier.citationBhattacharya T, Bhattacharya S, Ray AK, Dey S. Influence of industrial pollutants on thyroid function in Channa punctatus (Bloch). Indian Journal of Experimental Biology. 1989 Jan; 27(1): 65-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/58764
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAmmonia --toxicityen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCadmium --toxicityen_US
dc.subject.meshCadmium Chlorideen_US
dc.subject.meshEnvironmental Pollution --adverse effectsen_US
dc.subject.meshFishesen_US
dc.subject.meshMercuric Chloride --toxicityen_US
dc.subject.meshPeroxidases --physiologyen_US
dc.subject.meshPhenolen_US
dc.subject.meshPhenols --toxicityen_US
dc.subject.meshThyroid Gland --drug effectsen_US
dc.subject.meshThyroxine --biosynthesisen_US
dc.titleInfluence of industrial pollutants on thyroid function in Channa punctatus (Bloch).en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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