Pharmacological actions of Pongamia pinnata roots in albino rats.

Simple item page
dc.contributor.authorSingh, R Ken_US
dc.contributor.authorNath, Gen_US
dc.contributor.authorAcharya, S Ben_US
dc.contributor.authorGoel, R Ken_US
dc.date.accessioned2009-05-28T13:40:43Z
dc.date.available2009-05-28T13:40:43Z
dc.date.issued1997-08-01en_US
dc.description.abstractPongamia pinnata root has been advocated in Ayurveda for treatment of various inflammatory and infective conditions including ulcers. Sequential petroleum ether, benzene, chloroform, acetone and ethanolic extracts of P. pinnata roots when administered in the dose of 50 mg/kg, i.p. in rats was found to have anti-inflammatory, analgesic activity while pentobarbitone-induced 'sleep time' was reduced by all the extracts except petroleum ether which, however, enhanced it. They were also found to possess antiulcer effects when administered either by i.p. (45 min before) or oral route (45 min before or for 4 days) against restraint-stress or pylorus-ligated gastric ulcers in rats, the maximum protection being afforded by petroleum ether and ethanol extracts. The mechanism of antiulcer effect could either be due to decrease in acid-pepsin secretion and augmentation of mucin secretion as observed with ethanol extract, while petroleum ether extract might be producing the effect by virtue of its anti-stress activity.en_US
dc.description.affiliationDepartment of Pharmacology, Banaras Hindu University, Varanasi, India.en_US
dc.identifier.citationSingh RK, Nath G, Acharya SB, Goel RK. Pharmacological actions of Pongamia pinnata roots in albino rats. Indian Journal of Experimental Biology. 1997 Aug; 35(8): 831-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/59724
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshFemaleen_US
dc.subject.meshMaleen_US
dc.subject.meshMedicine, Ayurvedicen_US
dc.subject.meshMiceen_US
dc.subject.meshPlant Extracts --pharmacologyen_US
dc.subject.meshPlant Roots --chemistryen_US
dc.subject.meshPlants, Medicinalen_US
dc.subject.meshRatsen_US
dc.titlePharmacological actions of Pongamia pinnata roots in albino rats.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Experimental Biology