Prion diseases: A challenge to animal health.

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dc.contributor.authorDudhatra, G B
dc.contributor.authorMody, S K
dc.contributor.authorPatel, H B
dc.contributor.authorModi, C M
dc.contributor.authorKumar, Avinash
dc.contributor.authorAwale, M M
dc.date.accessioned2014-05-20T06:21:14Z
dc.date.available2014-05-20T06:21:14Z
dc.date.issued2011-12
dc.description.abstractPrion diseases are known as transmissible spongiform encephalopathies (TSE), a group of rare, rapidly progressive, and fatal neurologic diseases. The agents responsible for human and animal prion diseases are abnormal proteins (prion or proteinaceous infectious particle) that can trigger chain reactions causing normal proteins in the brain to change to the abnormal protein. These abnormal proteins are resistant to enzymatic breakdown, and they accumulate in the brain, leading to damage. All have long incubation periods followed by chronic neurological disease and fatal outcomes, have similar pathology limited to the CNS include convulsions, dementia, ataxia (balance and coordination dysfunction), and behavioral changes, and are experimentally transmissible to some other species.en_US
dc.identifier.citationDudhatra G B, Mody S K, Patel H B, Modi C M, Kumar Avinash, Awale M M. Prion diseases: A challenge to animal health. Journal of Applied Pharmaceutical Science. 2011 Dec; 1(10): 215-221.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/151060
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=331en_US
dc.subjectBovine spongiform encephalopathyen_US
dc.subjectChronic wasting diseaseen_US
dc.subjectExotic ungulate encephalopathyen_US
dc.subjectFeline spongiform encephalopathyen_US
dc.subjectMad cow diseaseen_US
dc.subjectPrionen_US
dc.subjectScrapieen_US
dc.subjectTransmissible mink encephalopathyen_US
dc.titlePrion diseases: A challenge to animal health.en_US
dc.typeArticleen_US
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