Papillon-Lefevre syndrome: Report of two cases in the same family.
dc.contributor.author | Nagaveni, N B | en_US |
dc.contributor.author | Suma, R | en_US |
dc.contributor.author | Shashikiran, N D | en_US |
dc.contributor.author | Subba Reddy, V V | en_US |
dc.date.accessioned | 2008-04-08 | en_US |
dc.date.accessioned | 2009-06-02T09:15:02Z | |
dc.date.available | 2008-04-08 | en_US |
dc.date.available | 2009-06-02T09:15:02Z | |
dc.date.issued | 2008-04-08 | en_US |
dc.description.abstract | Papillon-Lefevre syndrome is a very rare syndrome of autosomal recessive inheritance characterized by palmar-plantar hyperkeratosis and early onset of a severe destructive periodontitis, leading to premature loss of both primary and permanent dentitions. Various etiopathogenic factors are associated with the syndrome but a recent report has suggested that the condition is linked to mutations of the cathepsin C gene. Two cases of Papillon-Lefevre syndrome in the same family, having all of the characteristic features, are presented. An 11-year-old girl and a 9-year-old boy presented with the complaints of loose teeth. Both expressed hyperkeratosis of palms, soles, and knees. Severe generalized periodontal destruction, with mobility of teeth, was evident on intraoral examination; orthopantomograph examination showed severe generalized loss of alveolar bone in both the patients. | en_US |
dc.description.affiliation | Department of Pedodontics, College of Dental Sciences, Davangere - 577 004, Karnataka, India. nagavenishankar@indiatimes.com. | en_US |
dc.identifier.citation | Nagaveni NB, Suma R, Shashikiran ND, Subba Reddy VV. Papillon-Lefevre syndrome: Report of two cases in the same family. Journal of the Indian Society of Pedodontics and Preventive Dentistry. 2008 Apr-Jun; 26(2): 78-81 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/114761 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://medind.nic.in/jao/jaoaj.shtml | en_US |
dc.title | Papillon-Lefevre syndrome: Report of two cases in the same family. | en_US |
dc.type | Journal Article | en_US |
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