Streptomycetes from Marine Seaweeds: Their Antimicrobial and Antibiotic Potential.
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Date
2014-10
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Abstract
Recent research has increased our knowledge and understanding of the antimicrobial effect of marine
Streptomyces. In a systematic screening effect, Streptomyces isolates from different marine seaweeds were
investigated for antimicrobial activity against Vibrio pathogens (V. harveyji, V. parahemolyticus, V. vulnificus and V.
algniolyticus) and potentially active secondary metabolites. The different solvent extracts (Butanol, Ethyl acetate,
Methanol, hexane) of selected isolates were screened for their antivibrio activity by disc method. The Zone of
inhibition was measured in all extracts revealed a wide range of antimicrobial activity against pathogenic vibrios. The
overall results of the antimicrobial activity indicates the abundance of purine riboside antibiotic in streptomycetes
from marine seaweeds evidenced by the presence of precursor molecules such as guanosine, xanthosine in the
extractions of Streptomyces which can be exploited for the production of purine riboside antibiotics which are in use
of pharmaceutical industry.
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Keywords
Purine riboside antibiotics, Derivatives of antibiotics, Xanthosine, Guanosine, Seaweeds
Citation
Sridevi K, Dhevendaran K. Streptomycetes from Marine Seaweeds: Their Antimicrobial and Antibiotic Potential. International Journal of Applied Biology and Pharmaceutical Technology. 2014 Oct-Dec; 5(4): 74-79.