Effect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver--histological and histochemical study.

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dc.contributor.authorEl-Banhawey, Mahmoud Aen_US
dc.contributor.authorAshry, Madeha Aen_US
dc.contributor.authorEl-Ansary, Afaf Ken_US
dc.contributor.authorAly, Sanaa Aen_US
dc.date.accessioned2009-05-28T14:00:27Z
dc.date.available2009-05-28T14:00:27Z
dc.date.issued2007-10-24en_US
dc.description.abstractEffect of drug praziquantel (PZQ) and C. longa extract on S. mansoni infected mice is reported. The level of glycogen, alkaline and acid phosphatases (ALP and ACP respectively), and body weight, liver weight and liver weight/body weight ratio were studied in mice infected with S. mansoni. ALP level was increased after infection. C. longa treated mice showed marked reduction in ALP level more than after PZQ-treatment. C. longa enhanced the concentration of glycogen after being reduced by infection, while PZQ-treatment revealed more reduction. C. longa caused enhancement in body weight while PZQ treatment had no effect. The formation of granuloma around schistosome eggs in the liver produced inflammation. C. longa extract and PZQ were effective in reducing granuloma size in infected mice.en_US
dc.description.affiliationDepartment of Experimental Zoology, Faculty of Science, Ain Shams University, Cairo, Egypt.en_US
dc.identifier.citationEl-Banhawey MA, Ashry MA, El-Ansary AK, Aly SA. Effect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver--histological and histochemical study. Indian Journal of Experimental Biology. 2007 Oct; 45(10): 877-89en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/60149
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.source.urihttps://nopr.niscair.res.in/bitstream/123456789/5519/1/IJEB%2045%2810%29%20877-889.pdfen_US
dc.subject.meshAlkaline Phosphatase --metabolismen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBody Weight --drug effectsen_US
dc.subject.meshCurcuma --chemistryen_US
dc.subject.meshLiver Diseases --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshOrgan Size --drug effectsen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshPlant Extracts --chemistryen_US
dc.subject.meshPraziquantel --therapeutic useen_US
dc.subject.meshSchistosoma mansoni --physiologyen_US
dc.subject.meshSchistosomiasis mansoni --drug therapyen_US
dc.titleEffect of Curcuma longa or parziquantel on Schistosoma mansoni infected mice liver--histological and histochemical study.en_US
dc.typeJournal Articleen_US
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