A comparative evaluation of total antioxidant capacity of saliva in children with and without Gingivitis

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dc.contributor.authorKumar, Bharaten_US
dc.contributor.authorAfroz, Alam Ansarien_US
dc.contributor.authorTiwari, Sanchiten_US
dc.contributor.authorMohd, Waseemen_US
dc.contributor.authorSingh, Seemaen_US
dc.contributor.authorMahdi, A.A.en_US
dc.contributor.authorChak, Rakesh Kumaren_US
dc.date.accessioned2020-09-24T07:34:30Z
dc.date.available2020-09-24T07:34:30Z
dc.date.issued2019-06
dc.description.abstractGingivitis is a reversible and non-destructive form of periodontal disease. Oxidative stress contributes in the pathogenesis of periodontal diseases5. The oxidative stress has been implicated as one of the important contributory etiologic factors in many of the oral inflammatory pathologies including gingivitis. This research analyzed the "Total antioxidant capacity" (TAC) of biological fluids including saliva. The present cross-sectional study was conducted to evaluate the total antioxidant capacity (TAC) of saliva in children with/ without gingivitis and its relation with Age and Gender. For measuring the TAC of saliva: Cayman's Antioxidant Assay Kit was used and Gingival Index Measured through The Gingival Index (Löe and Silness, 1963). The results were analyzed using descriptive statistics and making comparisons between cases and control by using SPSS software version 20. In this result, mean TAC of saliva in case children group was found lower 0.203 ± 0.053 compared to control children group was higher 0.236 ± 0.048. While, in male and female children of aged 3-5 years were found antioxidant activity (TAC) lower in compared to control groups. But among males aged 6-13 years it was found that the mean antioxidant capacity of saliva in case group was 0.259 ± 0.040 while in control group it was 0.295 ± 0.026. The TAC of saliva in males was found high compared to female. A weak negative correlation was found between the TAC and gingival index. In conclusion TAC decreases in children with gingivitis compared to healthy children. The gingivitis was more observed in female leading to lower TAC valueen_US
dc.identifier.affiliationsDepartment of Pediatric and Preventive Dentistry, King George’s Medical University, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatric and Preventive Dentistry, King George’s Medical University, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, King George’s Medical University, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry , King George’s Medical University, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, King George’s Medical University, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, King George’s Medical University, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatric and Preventive Dentistry, King George’s Medical University, Lucknow, Indiaen_US
dc.identifier.citationKumar Bharat, Afroz Alam Ansari, Tiwari Sanchit, Mohd Waseem, Singh Seema, Mahdi A.A., Chak Rakesh Kumar. A comparative evaluation of total antioxidant capacity of saliva in children with and without Gingivitis. International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL). 2019 Jun; 8(3): 7-11en_US
dc.identifier.issn2282-0238
dc.identifier.issn2393-932X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203819
dc.languageenen_US
dc.publisherSociety for research and Development in Educationen_US
dc.relation.issuenumber3en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.21276/IJRDPL.2278-0238.2019.8(3).7-11en_US
dc.subjectDiabetic nephropathyen_US
dc.subjectGene polymorphismen_US
dc.subjectGlucose transporter geneen_US
dc.subjectRestriction fragment length poly-morphismen_US
dc.subjectType 2 Diabetes melitusen_US
dc.titleA comparative evaluation of total antioxidant capacity of saliva in children with and without Gingivitisen_US
dc.typeJournal Articleen_US
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