Update results of intrabifurcations of aorta infusion by high dosage mitomycin-C in uterine cervical squamous cell carcinoma stage II, III (Report of 35 cases).
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Date
1987-03
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Abstract
Thirty-five new patients with squamous cell carcinoma of the cervix stage II and III, with refusal of radiation therapy were treated with a single dose of mitomycin-C 35 mg/m2 intrabifurcation of the aorta infusion. 85.7 percent had clinically complete regression and 5.71 percent had partial regression. Twenty-seven cases of the clinically complete regression were treated by radical hysterectomy and pelvic nodes dissection. There were 10 cases (37.03%) showing pathologically complete regression, 11 cases (40.74%) showing small residual cancer in the cervix and 6 cases (22.22%) showing residual cancer in the cervix and pelvic nodes. The follow up performed after 18-30 months, revealed recurrence or metastases in 18.51 percent of the cases. Mild nausea, alopecia, weakness, anorexia, moderately depressed in the second week after treatment.
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Intrabifurcations, Aorta, Mitomycin-C, Uterine cervical squamous cell carcinoma
Citation
Senapad Sumrit, Vaeusorn N, Vootiprux V. Update results of intrabifurcations of aorta infusion by high dosage mitomycin-C in uterine cervical squamous cell carcinoma stage II, III (Report of 35 cases). Siriraj Medical Journal, 1987 Mar; 39(3): 125-133.