Tamoxifen increases the proliferation of human endometrial stromal cells in in vitro. A model for evaluation of endometrial hyperplasia.

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dc.contributor.authorBhargava Periwal, Sen_US
dc.contributor.authorFarooq, Aen_US
dc.contributor.authorBhargava, V Len_US
dc.contributor.authorBhatla, Nen_US
dc.contributor.authorVij, Uen_US
dc.contributor.authorMurugesan, Ken_US
dc.date.accessioned2009-05-28T14:48:26Z
dc.date.available2009-05-28T14:48:26Z
dc.date.issued1995-12-01en_US
dc.description.abstractTamoxifen given for breast cancer therapy, has a complex and an unclear action on the endometrium. A large number of literatures has attributed the proliferous changes in the endometrium caused by tamoxifen (Tam). No report has appeared on the endometrial cellular changes induced by Tam. The present study shows a significant (P < 0.001) increase in the proliferative activity due to Tam in endometrial stromal cells over control and estradiol (E2). This in vitro model is useful for the study of the hyperplasic effect of Tam at the cellular level.en_US
dc.description.affiliationDepartment of Reproductive Biology, All Indian Institute of Medical Sciences, Ansari Nagar, New Delhi.en_US
dc.identifier.citationBhargava Periwal S, Farooq A, Bhargava VL, Bhatla N, Vij U, Murugesan K. Tamoxifen increases the proliferation of human endometrial stromal cells in in vitro. A model for evaluation of endometrial hyperplasia. Indian Journal of Experimental Biology. 1995 Dec; 33(12): 977-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/61182
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshCell Division --drug effectsen_US
dc.subject.meshEndometrial Hyperplasia --chemically induceden_US
dc.subject.meshEndometrium --drug effectsen_US
dc.subject.meshEvaluation Studies as Topicen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshModels, Biologicalen_US
dc.subject.meshStromal Cells --drug effectsen_US
dc.subject.meshTamoxifen --pharmacologyen_US
dc.titleTamoxifen increases the proliferation of human endometrial stromal cells in in vitro. A model for evaluation of endometrial hyperplasia.en_US
dc.typeJournal Articleen_US
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