Immediate causes of death in AIDS patients admitted on principal diagnosis of cryptococcal meningitis or toxoplasma encephalitis at Chiangraiprachanukroh Hospital.

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Date
2000-04
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Abstract
Fifty-two AIDS patients with principal diagnosis of Crytococcal meningitis were dead (no autopsy) in the hospital, the ration of male to female was 1.7:1. 52 percent dead on 1st diagnosis and 1st admission duration between symptoms begun and dead average 15.27 days. 21.2 percent dead on 2nd or 3rd admission average time from 1st diagnosis to dead was 113.2 days. 3.8 percent showed clinical of chronic sepsis without eningoencephalitis average time until dead was 28.5 days 1.9 percent was dual fungal septicemia (C.neoformans and P.marneffei). 3.8 percent dual infection Cryptococcus combined with eoxoplasmosis. 9.7 percent dead from bran death but laboratory data to confirm diagnosis of Crytococcal meningitis were conflicted. 3.8 percent dead from hepatic failure (from anti TB drug), this patient develop pulm. And In. during maintenance Rx CM, or renal failure (from amphotericin). 3.8 percent dead from Salmonella gr. B sepsis or other new fungus (Cladophilophora bantiana). Fifteen AIDS patients with principal diagnosis of Toxoplasma encephalitis were dead (no autopsy) in the hospital, the ratio of male to female was 2:1. 46.7 percent dead from brain death average time from symptoms begun to dad was 16.6 days. 33.4 percent dead from severe thrombocytopenia (with massive lower G.I. hemorrhage or massive epistaxis) and / or severe leucopenia (with sepsis), which were side effect of pyrimethamine, average time to develop this side effect was 19 days and average time from symptoms of TE begun to dead was 37 days. 13.3 percent dead from pneumocystis carinii pneumonia or cavernous sinus thrombophlebitis. 6.6 percent dead from HIV encephalopathy with AIDS dementia complex.
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Keywords
Causes of Death, AIDS, Cryptococcal Meningitis, Toxoplasma Encephalitis
Citation
Toemthong Reuchukorn. Immediate causes of death in AIDS patients admitted on principal diagnosis of cryptococcal meningitis or toxoplasma encephalitis at Chiangraiprachanukroh Hospital. Siriraj Medical Journal, 2000 Apr; 52(4): 226-231.