Characterization of dopamine receptors involved in central thermoregulation in rabbits.

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dc.contributor.authorSrivastava, A Ken_US
dc.contributor.authorSrivastava, Y Pen_US
dc.contributor.authorGupta, P Pen_US
dc.contributor.authorVerma, R Ben_US
dc.date.accessioned2009-05-28T11:33:43Z
dc.date.available2009-05-28T11:33:43Z
dc.date.issued1991-11-01en_US
dc.description.abstractIntracerebroventricularly administered dopamine produced dose dependent hyperthermia in rabbits. Haloperidol, a D1 receptor blocker produced consistent hypothermia, whereas D2 receptor blocker metoclopramide produced hyperthermia, pretreatment with haloperidol competitively blocked the hyperthermic response of dopamine. Pretreatment with metoclopramide augmented the onset and peak response of dopamine. It is suggested that D1 receptors are involved in producing hyperthermia and D2 receptors in hypothermia.en_US
dc.description.affiliationDepartment of Pharmacology & Therapeutics, BRD Medical College, Gorakhpur, India.en_US
dc.identifier.citationSrivastava AK, Srivastava YP, Gupta PP, Verma RB. Characterization of dopamine receptors involved in central thermoregulation in rabbits. Indian Journal of Experimental Biology. 1991 Nov; 29(11): 1087-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56886
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBody Temperature Regulation --drug effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHaloperidol --pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMetoclopramide --pharmacologyen_US
dc.subject.meshRabbitsen_US
dc.subject.meshReceptors, Dopamine --physiologyen_US
dc.titleCharacterization of dopamine receptors involved in central thermoregulation in rabbits.en_US
dc.typeJournal Articleen_US
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