Evaluation of prescribing pattern of drugs use in patients of coronary artery disease at a tertiary care hospital

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dc.contributor.authorBelhekar, Mahesh N.en_US
dc.contributor.authorPatel, Tejal C.en_US
dc.contributor.authorSingh, Mohit Kumaren_US
dc.contributor.authorPandit, Prasad R.en_US
dc.contributor.authorBhave, Kiran A.en_US
dc.contributor.authorRedkar, Neelam N.en_US
dc.date.accessioned2020-04-23T07:51:34Z
dc.date.available2020-04-23T07:51:34Z
dc.date.issued2018-09
dc.description.abstractBackground: Coronary artery disease (CAD) is a major cause responsible for mortality more in younger age group than in elderly. Studies have reported underuse of four evidence based medicines namely aspirin, β-blockers, angiotensin-converting enzyme inhibitors (ACE-I) or angiotensin receptor blockers (ARB), and statins in patients with CAD, particularly in developing countries. Therefore, this study was planned to analyse the prescriptions of patients with CAD to determine the appropriateness of the prescriptions.Methods: After obtaining the Institutional ethics committee permission, a cross sectional observational study was conducted at a tertiary care hospital. Total 150 patients were enrolled from the outpatient department, wards and intensive care unit of medicine department. Total 150 patients’ prescriptions presenting with varied category of CAD were screened and analysed.Results: The most common categories of CAD encountered was ST segment elevated myocardial infarction (N=50, 33%) followed by chronic stable angina (N=29, 20%). Among the drugs prescribed, antiplatelet drugs were prescribed to 135 (90%), hypolipidemics to 134 (89%), nitrates to 114 (76%), beta blockers to 97 (65%), ACE inhibitors to 94 (64%), anticoagulants to 60 (40%) and miscellaneous drugs to 52 (35%), patients. Of 68 (45%) patients with type 2 diabetes mellitus, 15 (22%) were prescribed only metoprolol and others were given ACE-I or ARBs.Conclusions: Among four evidence based drugs, use of 3 drugs, antiplatelets, beta blockers and hypolipidemics was apparent in 90% of prescriptions. Use of ACE inhibitors and ARBs was observed in type 2 diabetic patients with CAD, reflecting rational prescribing behavior of clinicians.en_US
dc.identifier.affiliationsDepartment of Pharmacology, HBT Medical College and Dr. RN Cooper Municipal General Hospital, Mumbai, Maharashtra Province, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, HBT Medical College and Dr. RN Cooper Municipal General Hospital, Mumbai, Maharashtra Province, Indiaen_US
dc.identifier.citationBelhekar Mahesh N., Patel Tejal C., Singh Mohit Kumar, Pandit Prasad R., Bhave Kiran A., Redkar Neelam N.. Evaluation of prescribing pattern of drugs use in patients of coronary artery disease at a tertiary care hospital. International Journal of Basic & Clinical Pharmacology. 2018 Sep; 7(9): 1792-1796en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/199835
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2319-2003.ijbcp20183491en_US
dc.subjectMyocardial infarctionen_US
dc.subjectObservational studyen_US
dc.subjectPrescription auditingen_US
dc.subjectSecondary preventionen_US
dc.titleEvaluation of prescribing pattern of drugs use in patients of coronary artery disease at a tertiary care hospitalen_US
dc.typeJournal Articleen_US
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