Antibiotic Use In Pediatric Infections; A Study In Tertiary Care Hospital

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dc.contributor.authorGungam, Praveenaen_US
dc.contributor.authorYadav, Y. Sunil Kumaren_US
dc.contributor.authorJunapudi, Sunilen_US
dc.date.accessioned2020-05-05T07:06:13Z
dc.date.available2020-05-05T07:06:13Z
dc.date.issued2018-10
dc.description.abstractObjectives:Antibiotics are frequently used in tertiary care hospitals. We conducted an observational study on chil-dren admitted to a teaching hospital in south India, to make a profile of antibiotics use and suspected adverse drug reactions (ADRs) owing to them. Methods:Hospitalized children of either sex, aged between 1 month and 12 years, were inspected. Baseline demographic and clinical features, duration of hospital stay, antibiotics received in hospital along with dosing and indications and interest of suspected ADRs attributable to their use were recorded. Every pa-tient was followed up till discharge, admission to the Pediatric Intensive Care Unit, or passing. Results:Over the year and a half report period 364 confirmations were screened. The prevalence of Antibiotics use was 80.22%. The majori-ty of the 292 children who received Antibiotics were males (63.35%). Median age was 35 months, five children died. In most instances, either two (41%) or a single antibiotic (37.32%) was used. Ceftriaxone, co-amoxiclav, amikacin, vancomycin, and ampicillin were predominantly used. Antimalarials, antivirals and antiprotozoals were used occa-sionally. Average number of Antibiotics per patient was 2.2± 1.1 the majority (81.15%) were by parenteral route and initial choice was usually empirical. Prescriptions were usually in generic name. The antibiotic treatment went some-where in the range of 1 and 32days, with a middle of 8 days. Five ADRs were noted of which half were skin rash and the rest loose stools. Conclusions:The profile of Antibiotic utilize is comprehensively like prior Indian investigations. Apparent overuse of multiple Antibiotics per prescription and the parenteral route requires exploration. Antibiotics are being used empirically in the absence of policy. ADRs to Antibiotics are occasional and usually mild. The bench-mark information can serve in situation analysis for antibiotic prescribing guidelines.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Osmania Medical College, Koti, Hyderabad, Telangana, India - 500095.en_US
dc.identifier.affiliationsDept. of. Pharmaceutical Chemistry, Geethanjali College of Pharmacy, Cherryal, Keesara, Medchal, Telangana, India -501301en_US
dc.identifier.citationGungam Praveena, Yadav Y. Sunil Kumar, Junapudi Sunil. Antibiotic Use In Pediatric Infections; A Study In Tertiary Care Hospital. International Journal of Clinical and Biomedical Research. 2018 Oct; 4(4): 26-32en_US
dc.identifier.issn2395-0471
dc.identifier.issn2521-0394
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200833
dc.languageenen_US
dc.publisherSumathi Publicationsen_US
dc.relation.issuenumber4en_US
dc.relation.volume4en_US
dc.source.urihttps://www.doi.org/10.31878/ijcbr.2018.44.06en_US
dc.subjectAntibioticen_US
dc.subjectPediatric infectionsen_US
dc.subjectAdverse drug reactionsen_US
dc.subjectTertiary care hospitalen_US
dc.titleAntibiotic Use In Pediatric Infections; A Study In Tertiary Care Hospitalen_US
dc.typeJournal Articleen_US
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