Effect of intracerebroventricular administration of angiotensin II on emetic reflex in dogs.

dc.contributor.authorGupta, Y Ken_US
dc.contributor.authorChugh, Aen_US
dc.contributor.authorBhandari, Pen_US
dc.contributor.authorSeth, S Den_US
dc.date.accessioned2009-05-28T12:57:43Z
dc.date.available2009-05-28T12:57:43Z
dc.date.issued1989-06-01en_US
dc.description.abstractArea postrema is rich in angiotensin II receptors and intravenous (iv) administration of angiotensin II has been reported to elicit emesis. However, in the present study intracerebroventricular (icv) administration of angiotensin II up to a dose of 10 micrograms failed to elicit emesis. It is suggested that presence of a cerebrospinal fluid-brain barrier in area postrema most probably prevents access of icv angiotensin II to its receptors which are otherwise accessible on iv administration.en_US
dc.identifier.citationGupta YK, Chugh A, Bhandari P, Seth SD. Effect of intracerebroventricular administration of angiotensin II on emetic reflex in dogs. Indian Journal of Experimental Biology. 1989 Jun; 27(6): 576-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/58780
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAngiotensin II --administration & dosageen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBrain --drug effectsen_US
dc.subject.meshDogsen_US
dc.subject.meshFemaleen_US
dc.subject.meshInjections, Intraventricularen_US
dc.subject.meshMaleen_US
dc.subject.meshReflex --drug effectsen_US
dc.subject.meshVomitingen_US
dc.titleEffect of intracerebroventricular administration of angiotensin II on emetic reflex in dogs.en_US
dc.typeJournal Articleen_US
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