Synthesis and antifungal activity of 6-bromo-2[(4-(2,3-dichlorophenyl)) piperazine-1-yl)methyl]-3-[8-hydroxy quinoline -5-yl]-3-quinazolin -4-one ligand and its transition metal chelates.

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dc.contributor.authorVashi, R T
dc.contributor.authorShelat, C D
dc.contributor.authorPatel, Himanshu
dc.date.accessioned2015-06-23T05:58:42Z
dc.date.available2015-06-23T05:58:42Z
dc.date.issued2010-11
dc.description.abstractThe present investigation involved the synthesis of novel ligand HL14 and its chelate complexes with Cu(II), Ni(II), Co(II), Mn (II) and Zn(II). The characterization studies of chelates were conducted using various physicochemical methods such as elemental analysis, conductometric studies, magnetic susceptibility, FT-IR, NMR and electronic spectral data. The stoichiometry of the complex has been carried out and found to be 1: 2 (Metal: ligand). An octahedral geometry around Co (II), Ni (II) and Mn (II), distorted octahedral geometry around Cu (II) and tetra hedral geometry around Zn(II) have been proposed. The antifungal activity of ligand and its metal chelates was performed against various fungi.en_US
dc.identifier.citationVashi R T, Shelat C D, Patel Himanshu. Synthesis and antifungal activity of 6-bromo-2[(4-(2,3-dichlorophenyl)) piperazine-1-yl)methyl]-3-[8-hydroxy quinoline -5-yl]-3-quinazolin -4-one ligand and its transition metal chelates. International Journal of Applied Biology and Pharmaceutical Technology. 2010 Nov-Dec; 1(3): 883-889.en_US
dc.identifier.issn0976-4550
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/158200
dc.language.isoenen_US
dc.source.urihttps://www.ijabpt.com/pdf/68019-RT%20Vashi-HL4.pdfen_US
dc.subject8-Hydroxy quinoline liganden_US
dc.subjectComplexesen_US
dc.subjectElectronicen_US
dc.subjectNMR spectral studiesen_US
dc.subjectAntifungal activityen_US
dc.titleSynthesis and antifungal activity of 6-bromo-2[(4-(2,3-dichlorophenyl)) piperazine-1-yl)methyl]-3-[8-hydroxy quinoline -5-yl]-3-quinazolin -4-one ligand and its transition metal chelates.en_US
dc.typeArticleen_US
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