A case of acute myeloid leukemia-M2 with trisomy 4 in addition to t(8;21).
| dc.contributor.author | Trivedi, P J | |
| dc.contributor.author | Patel, P S | |
| dc.contributor.author | Brahmbhatt, M M | |
| dc.contributor.author | Patel, B P | |
| dc.contributor.author | Gajjar, S B | |
| dc.contributor.author | Iyer, R R | |
| dc.contributor.author | Parikh, E H | |
| dc.contributor.author | Shukla, S N | |
| dc.contributor.author | Shah, P M | |
| dc.contributor.author | Bakshi, S R | |
| dc.date.accessioned | 2012-06-05T10:26:44Z | |
| dc.date.available | 2012-06-05T10:26:44Z | |
| dc.date.issued | 2008-01 | |
| dc.description.abstract | t(8;21)(q22;q22) is the most frequently observed karyotypic abnormality associated with acute myeloid leukemia (AML), specifically in FAB-M2. Short-term unstimulated bone marrow (BM) and peripheral blood lymphocyte culture showed 47,XX, +4,t(8;21) in all metaphase plates; and interphase and metaphase results of AML-ETO fusion was positive and trisomy of 4 was confirmed with WCP probes. Trisomy 4 in AML with t(8;21) is a rare numerical abnormality. Here we present such case of patient which may constitute a distinctive subtype. | en_US |
| dc.identifier.citation | Trivedi P J, Patel P S, Brahmbhatt M M, Patel B P, Gajjar S B, Iyer R R, Parikh E H, Shukla S N, Shah P M, Bakshi S R. A case of acute myeloid leukemia-M2 with trisomy 4 in addition to t(8;21). Indian Journal of Human Genetics. 2008 Jan; 14(1): 20-22. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/138845 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840780/ | en_US |
| dc.subject | Acute myeloid leukemia | en_US |
| dc.subject | cytogenetics | en_US |
| dc.subject | fluorescence in situ hybridization | en_US |
| dc.title | A case of acute myeloid leukemia-M2 with trisomy 4 in addition to t(8;21). | en_US |
| dc.type | Article | en_US |