Systemic sclerosis and tuberculosis A case report

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dc.contributor.authorGanesh, S. Umaen_US
dc.contributor.authorKrishnapriya, Ren_US
dc.contributor.authorSrinivasan, R.en_US
dc.date.accessioned2019-12-02T10:00:22Z
dc.date.available2019-12-02T10:00:22Z
dc.date.issued2017
dc.description.abstractScleroderma is a chronic systemic autoimmune disease of unknown origin characterized by excessive collagen deposition and autoantibodies. Patients with autoimmune diseases are known to develop infections like tuberculosis due to the disease per se and also secondary to immunosuppressive treatment. Mycobacterial infections are also known to induce the development of autoantibodies. We present a case of simultaneous occurrence of interstitial lung disease and pulmonary tuberculosis (BAL positive for AFB) in a patient with features of systemic sclerosis. Antibody profile was done were found to be positive for ANA. She also had most of the classical features of scleroderma on clinical examination thus confirming the diagnosis. A detailed history, clinical examination, radiological examination, bronchoscopy and immunological test helped in the diagnosis of the patient. We highlight the importance of suspicion, careful general examination, radiological assessment and screening tuberculosis patients for autoantibody profile in presence of a multisystem involvement.en_US
dc.identifier.affiliationsPost Graduate Student, Department of Respiratory Medicine, Meenakshi Medical College and Research Institute, Enathur, Kanchipuram, India, umaganesh@rocketmail.comen_US
dc.identifier.affiliationsAssociate Professor, Department of Respiratory Medicine, Meenakshi Medical College and Research Institute, Enathur, Kanchipuram, Indiaen_US
dc.identifier.affiliationsProfessor and Head, Department of Respiratory Medicine, Meenakshi Medical College and Research Institute, Enathur, Kanchipuram, Indiaen_US
dc.identifier.citationGanesh S. Uma, Krishnapriya R, Srinivasan R.. Systemic sclerosis and tuberculosis A case report. International Archives of Integrated Medicine. 2017 Oct; 4(10):en_US
dc.identifier.issn2394-0026
dc.identifier.issn2394-0034
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/186768
dc.languageenen_US
dc.publisherEducational Society for Excellenceen_US
dc.relation.issuenumber10en_US
dc.relation.volume4en_US
dc.subjectSystemic sclerosisen_US
dc.subjectTuberculosisen_US
dc.subjectANAen_US
dc.titleSystemic sclerosis and tuberculosis A case reporten_US
dc.typeJournal Articleen_US
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