Pseudocholinesterase As A Predictor Marker In Hypothyroid Patients

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dc.contributor.authorKaushik, GGen_US
dc.contributor.authorSoni, Reenaen_US
dc.date.accessioned2020-05-05T07:06:11Z
dc.date.available2020-05-05T07:06:11Z
dc.date.issued2018-07
dc.description.abstractIntroduction: Hypothyroidism is due to decreased circulating levels of Thyroid hormones and is caused by inade-quate functioning of thyroid gland. Pseudocholinesterase (PCHE) is a nonspecific cholinesterase enzyme that hydro-lyses choline based esters in plasma. The purpose of this study was to evaluate the serum level of PCHE in hypothy-roid patients. Methodology:The present study was conducted on 100 newly diagnosed hypothyroid patients attend-ing the Medical OPD. The results of patients were compared with 100 healthy controls of either sex of similar age group. Anthropometric measurements, T3, T4, TSH, PCHE & Cholesterol estimations were performed. Results:The mean serum PCHE (decrease) level was observed statistically highly significant (p<0.001) in hypothyroid patients as compared with healthy control subjects. A highly significant positive correlation between PCHE with T3 & T4 (p< 0.001) in hypothyroid cases. Conclusion:Serum Pseudocholinesterase may be helpful as biomarker in screening test for hypothyroidism along with thyroid stimulating hormone.en_US
dc.identifier.affiliationsSr.Professor & HOD, J.L.N. Medical College, Ajmer, Rajasthan, India.en_US
dc.identifier.affiliationsResident, Department of Biochemistry, J.L.N. Medical College, Ajmer, Rajasthan, India.en_US
dc.identifier.citationKaushik GG, Soni Reena . Pseudocholinesterase As A Predictor Marker In Hypothyroid Patients . International Journal of Clinical and Biomedical Research. 2018 Jul; 4(3): 27-29en_US
dc.identifier.issn2395-0471
dc.identifier.issn2521-0394
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200816
dc.languageenen_US
dc.publisherSumathi Publicationsen_US
dc.relation.issuenumber3en_US
dc.relation.volume4en_US
dc.source.urihttps://www.doi.org/10.31878/ijcbr.2018.43.06en_US
dc.subjectHypothyroidismen_US
dc.subjectThyroid Profileen_US
dc.subjectPseudocholinesteraseen_US
dc.titlePseudocholinesterase As A Predictor Marker In Hypothyroid Patientsen_US
dc.typeJournal Articleen_US
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