Persistently elevated serum transcobalamin II in a patient with reactive haemophagocytic syndrome.
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Date
1997-07
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Abstract
A 24-year-old man was admitted to the hospital with a history of prolonged fever, peripheral blood neutropenia and bone marrow showing benign haemophagocytic histiocytosis. He presented with symptoms and manifestations over a brief duration until death, with the progressive development of multi-organ dysfunction. His serum TCII levels were persistently elevated throughout the disease duration in the hospital. Available evidence indicates that macrophages, mononuclear cells and histiocytes can produce TCII. Serum TCII levels in patients with reactive haemophagocytic syndrome are therefore elevated due to the increased be helpful in making the diagnosis in these patients.
Description
Keywords
Serum transcobalamin II, Reactive haemophagocytic syndrome
Citation
Areekul Suvit, Cheeramakara Cheeraratna, Paksanond Suporn, Songmuaeng Kriyaporn, Sukchut Bangon, Pienpicharn Duangduen, Wilairatana Polrat. Persistently elevated serum transcobalamin II in a patient with reactive haemophagocytic syndrome. Siriraj Medical Journal, 1997 Jul; 49(7): 656-660.