Early diagnosis of cancer in renal transplant patients: a single center experience.

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dc.contributor.authorYildirim, Yesimen_US
dc.contributor.authorOzyilkan, Ozguren_US
dc.contributor.authorEmiroglu, Remzien_US
dc.contributor.authorDemirhan, Beyhanen_US
dc.contributor.authorKarakayali, Hamdien_US
dc.contributor.authorHaberal, Mehmeten_US
dc.date.accessioned2009-05-27T17:43:08Z
dc.date.available2009-05-27T17:43:08Z
dc.date.issued2006-04-15en_US
dc.descriptionAsian Pacific Journal of Cancer Prevention. 30 references.en_US
dc.description.abstractRenal transplantation confers increased survival with improvement of immune suppressive drugs, but certain types of neoplasm can arise as secondary complications. It is thus well known that recipients have significantly increased risk of developing de novo malignancy when compared with the age-matched general population. Cancer is the 4th most common cause of death in transplant patients after cardiovascular disease, infections and liver failure. Our transplantation team has performed 1,582 kidney transplantations since 1975. Fifty-nine of the patients developed malignancies in the posttransplantation period. The most common was Kaposi's sarcoma (19 patients, 32.2 %), followed by lymphomas (16 patients, 27.1 %) and skin carcinomas (13 patients, 22.0 %). Many factors can contribute to high susceptibility in these patients; age at transplantation, certain types of viral infections like Epstein-Barr virus, human herpes virus-8, human papilloma virus or chronic usage of immune suppressive agents, type of immune suppressive drugs, and ethnic characteristics. Transplant recipients generally have advanced stage cancers at the time of diagnosis with a poor prognosis. Since some neoplasms are common early detection of cancer is important to decrease cancer related mortality and morbidity. This article considers risk factors and recommendations for early diagnosis of cancer in renal transplant patients.en_US
dc.description.affiliationBaskent University Faculty of Medicine, TR 06490 Ankara, Turkey. dryesimyildirim@yahoo.comen_US
dc.identifier.citationYildirim Y, Ozyilkan O, Emiroglu R, Demirhan B, Karakayali H, Haberal M. Early diagnosis of cancer in renal transplant patients: a single center experience. Asian Pacific Journal of Cancer Prevention. 2006 Apr-Jun; 7(2): 336-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/37744
dc.language.isoengen_US
dc.source.urihttps://www.apocp.orgen_US
dc.subject.meshEarly Diagnosisen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunosuppressive Agents --adverse effectsen_US
dc.subject.meshKidney Diseases --surgeryen_US
dc.subject.meshKidney Transplantation --adverse effectsen_US
dc.subject.meshNeoplasms --diagnosisen_US
dc.subject.meshPractice Guidelines as Topicen_US
dc.subject.meshRisk Factorsen_US
dc.titleEarly diagnosis of cancer in renal transplant patients: a single center experience.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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