Uncovering the diuretic potential of Abutilon hirtum leaves extract in wistar albino rats

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dc.contributor.authorNalawade, VVen_US
dc.contributor.authorShirote, PJ.en_US
dc.date.accessioned2025-08-13T08:58:30Z
dc.date.available2025-08-13T08:58:30Z
dc.date.issued2025-02
dc.description.abstractAbutilon hirtum, traditionally recognized for its alleged diuretic effects, underwent examination to assess its viability as a natural substitute for synthetic diuretics. The methanolic extract of A. hirtum leaves (AHME) was methodically prepared using Soxhlet extraction technique and assessed for its diuretic activity in wistar albino rats. Five different groups were created from the animals: a control group, a standard group that received furosemide, and three test groups that received 150, 300 and 450 mg/kg of body weight of AHME. The evaluation of diuretic activity was conducted through the lipschitz test, which involved measuring various parameters including urine volume, pH, electrolyte excretion, diuretic effect and lipschitz value. The highest dose (450 mg/kg) substantially raised urine volume, electrolyte excretion, and pH compared to the control, with a Lipschitz value of 2.35. These results corroborate the traditional use of A. hirtum leaves and provide a basis to subsequent pharmacological research by confirming their diuretic ability.en_US
dc.identifier.affiliationsAppasaheb Birnale College of Pharmacy, Sangli, Maharashtra, Indiaen_US
dc.identifier.affiliationsDr. Bapuji Salunkhe Institute of Pharmacy, Miraj, Maharashtra, Indiaen_US
dc.identifier.citationNalawade VV, Shirote PJ.. Uncovering the diuretic potential of Abutilon hirtum leaves extract in wistar albino rats. International Journal of Pharmaceutical Sciences and Drug Research . 2025 Feb; 17(1): 30-34en_US
dc.identifier.issn0975 – 248X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/250342
dc.languageenen_US
dc.publisherMRI Publication Pvt. Ltd.en_US
dc.relation.issuenumber1en_US
dc.relation.volume17en_US
dc.source.urihttps://doi.org/10.25004/IJPSDR.2025.170105en_US
dc.subjectAbutilon hirtumen_US
dc.subjectfolkloreen_US
dc.subjectmethanolen_US
dc.subjectlipschitz modelen_US
dc.subjectdiuretic activityen_US
dc.titleUncovering the diuretic potential of Abutilon hirtum leaves extract in wistar albino ratsen_US
dc.typeJournal Articleen_US
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