Direct Immunofluorescence Profile Of Lichen Planus - A Fresh Look On Old Disease. A Study Of 15 Cases

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Date
2018-08
Journal Title
Journal ISSN
Volume Title
Publisher
World Wide Journals
Abstract
Introduction: Lichen planus (LP) is a chronic inflammatory mucocutaneous diasease that is often diagnosed on the basis of clinical &/or histopathologic findings. However, it has some characteristic direct immunofluorescence (DIF) findings that can help in diagnosing confusing cases.Aim:We analyzed DIF findings in skin biopsy in LP compared to histopathology. Materials & methods: A skin biopsy of lesion was taken from 15 cases of LP(13 classic LP & 2 LP pigmentosus) & subjected to histopathology & DIF examination. Results:The sensitivity of histopathology and DIF was found to be 100% & 93.3% respectivelyfor the diagnosis of LP & LPP.
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Keywords
Direct immunofluorescence, Lichen planus, skin biopsy
Citation
Singh Deeksha, Agarwal Shilpi, Chander Ram, Agarwal Kiran, Singh Preksha. Direct Immunofluorescence Profile Of Lichen Planus - A Fresh Look On Old Disease. A Study Of 15 Cases. Global Journal For Research Analysis. 2018 Aug; 7(8): 26-28