Effect of alpha,beta-arteether against primary amoebic meningoencephalitis in Swiss mice.

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dc.contributor.authorGupta, Sen_US
dc.contributor.authorDutta, G Pen_US
dc.contributor.authorVishwakarma, R Aen_US
dc.date.accessioned2009-05-28T14:48:57Z
dc.date.available2009-05-28T14:48:57Z
dc.date.issued1998-08-05en_US
dc.description.abstractArtemisinin and its derivative alpha, beta-arteether have been evaluated for activity against experimental primary amoebic meningoencephalitis. In vivo experiments have shown that amphotericin B at dose of 2.5 mg/kg for 5 days produced 100% protection. Artemisinin and alpha, beta-arteether, even when tested at a high doses (60-120 mg/kg x 5 days and 90-180 mg/x 5 days) respectively, were not curative and showed only slight protection as indicated by extension of mean survival time.en_US
dc.description.affiliationCentre Drug Research Institute, Lucknow, India.en_US
dc.identifier.citationGupta S, Dutta GP, Vishwakarma RA. Effect of alpha,beta-arteether against primary amoebic meningoencephalitis in Swiss mice. Indian Journal of Experimental Biology. 1998 Aug; 36(8): 824-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/61193
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAmebiasis --drug therapyen_US
dc.subject.meshAmebicides --administration & dosageen_US
dc.subject.meshAmphotericin B --administration & dosageen_US
dc.subject.meshAnimalsen_US
dc.subject.meshArtemisininsen_US
dc.subject.meshMeningoencephalitis --drug therapyen_US
dc.subject.meshMiceen_US
dc.subject.meshNaegleria fowleri --isolation & purificationen_US
dc.subject.meshSesquiterpenes --administration & dosageen_US
dc.titleEffect of alpha,beta-arteether against primary amoebic meningoencephalitis in Swiss mice.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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