Lack of prognostic significance of HER-2/neu in early epithelial ovarian cancer.

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dc.contributor.authorSueblinvong, Thanasaken_US
dc.contributor.authorManchana, Tarineeen_US
dc.contributor.authorKhemapech, Niponen_US
dc.contributor.authorTriratanachat, Surangen_US
dc.contributor.authorTermrungruanglert, Wichaien_US
dc.contributor.authorTresukosol, Damrongen_US
dc.date.accessioned2009-05-27T17:40:07Z
dc.date.available2009-05-27T17:40:07Z
dc.date.issued2007-10-12en_US
dc.descriptionAsian Pacific Journal of Cancer Prevention.en_US
dc.description.abstractA total of 74 patients with apparent early stage epithelial ovarian cancer who underwent exploratory laparotomy at King Chulalongkorn Memorial Hospital or other hospitals and were referred for further treatment, were evaluated. Formalin fixed paraffin-embedded ovarian tissue specimens were collected and immuno-stained with HER-2/neu antibodies for comparison with clinicopathologic data after median follow up of 46 months (range 3 - 83 months). The prevalence of HER-2/neu overexpression in these patients was 10.2%. No significant correlation between HER-2/neu overexpression and clinicopathological parameters (stage, ascites, capsular rupture, capsular adherence, histological subtype and histological grade) was found. Disease free survival and overall survival did not statistically differ between those with lesions positive or negative for HER-2/neu overexpression.en_US
dc.description.affiliationsthanasak@yahoo.comen_US
dc.identifier.citationSueblinvong T, Manchana T, Khemapech N, Triratanachat S, Termrungruanglert W, Tresukosol D. Lack of prognostic significance of HER-2/neu in early epithelial ovarian cancer. Asian Pacific Journal of Cancer Prevention. 2007 Oct-Dec; 8(4): 502-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/37635
dc.language.isoengen_US
dc.source.urihttps://www.apocp.orgen_US
dc.subject.meshAdenocarcinoma, Clear Cell --metabolismen_US
dc.subject.meshAdenocarcinoma, Mucinous --metabolismen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCarcinoma, Endometrioid --metabolismen_US
dc.subject.meshCell Membrane --metabolismen_US
dc.subject.meshCystadenocarcinoma, Serous --metabolismen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoenzyme Techniquesen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Recurrence, Local --diagnosisen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshOvarian Neoplasms --diagnosisen_US
dc.subject.meshParaffin Embeddingen_US
dc.subject.meshPrognosisen_US
dc.subject.meshReceptor, erbB-2 --metabolismen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTumor Markers, Biological --metabolismen_US
dc.titleLack of prognostic significance of HER-2/neu in early epithelial ovarian cancer.en_US
dc.typeJournal Articleen_US
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