Platelet Distribution Width (PDW) in Thrombocytopenia.

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dc.contributor.authorReddy, R. Shridhar
dc.contributor.authorKhan, Mohd Inayatulla
dc.contributor.authorPhansalkar, Manjiri Dilip
dc.date.accessioned2016-12-15T04:38:31Z
dc.date.available2016-12-15T04:38:31Z
dc.date.issued2015-05
dc.description.abstractBackground: Platelet volume parameters are significant especially in diagnosis of causes of thrombocytopenia. The platelet parameters are widely available as part of full blood count with no extra cost. Thrombocytopenia is of varying etiology based on which it is broadly divided into three major categories (1) as increased destruction, (2) decreased production and (3) splenic sequestration/abnormal pooling. The present study was undertaken to understand relation between cause of thrombocytopenia and Platelet Distribution Width as well as other platelet parameters. Materials and Methods: 500 cases of Thrombocytopenia (TCP) and 300 control cases having normal platelet count were selected. TCP was defined as platelet count <1.5lakh/ìl. Analysis was done by Sysmex KX 21 cell counter and every case was reassessed by Peripheral Smear (P.S.) examination and if necessary also by manual method. Only those cases that had sufficient clinico-hematological work -up and the causes of low platelet count had been reliably established were included in the study. Results: The study was conducted on 500 cases they were broadly categorized into three groups Group A with accelerated platelet Destruction Group B with Impaired production and Group C with abnormal pooling. Out of 500 cases 272 (54%) were male and 228(46%) were female. A slight male preponderance was seen in overall picture as well as in almost all age groups. The overall male to female ratio being 1.19 : 1. Mean platelet volume [MPV] was statistically significant with ‘p’ valuesen_US
dc.identifier.citationReddy R. Shridhar, Khan Mohd Inayatulla, Phansalkar Manjiri Dilip. Platelet Distribution Width (PDW) in Thrombocytopenia. Indian Medical Gazette. 2015 May; 149(5):169-173.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/179857
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/ice/t15/i5/icet15i5p169.pdfen_US
dc.subjectthrombocytopenia [TCP]en_US
dc.subjectmean platelet volume [MPV]en_US
dc.subjectplatelet distribution width [PDW]en_US
dc.titlePlatelet Distribution Width (PDW) in Thrombocytopenia.en_US
dc.typeArticleen_US
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