Mechanism of histamine induced dispersal response in the isolated web melanophores of a frog, Rana tigerina (Daud.).

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dc.contributor.authorOvais, Men_US
dc.contributor.authorChimania, S Ren_US
dc.date.accessioned2009-05-28T15:28:58Z
dc.date.available2009-05-28T15:28:58Z
dc.date.issued1995-05-01en_US
dc.description.abstractEffects of histamine and specific H1, H2 receptor agonists have been investigated on the isolated web skin melanophores of the frog, R. tigerina. Histamine, 2-methyl-histamine and 4-methyl-histamine all induced dose dependent dispersion in the frog melanophores. Reserpine treatment of the frog skin, either in vivo, or in vitro potentiated the dispersal response of the frog skin melanophores elicited by histamine. Histamine induced dispersal responses in the frog integumentary melanophores were partially blocked by mepyramine and ranitidine. Atropine failed to inhibit the dispersal response in any degree. Propranolol partially inhibited the dispersion of frog melanophores induced by histamine and 2-methyl-histamine. However, propranolol completely blocked the dispersal response of the mealnophores to 4-methyl-histamine. It is suggested that histamine induced dispersion in the frog skin melanophores in vitro is mediated partially through specific H1, H2 and beta adrenergic receptors.en_US
dc.description.affiliationDepartment of Biosciences, Barkatullah University, Bhopal, India.en_US
dc.identifier.citationOvais M, Chimania SR. Mechanism of histamine induced dispersal response in the isolated web melanophores of a frog, Rana tigerina (Daud.). Indian Journal of Experimental Biology. 1995 May; 33(5): 348-52en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62033
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHistamine --pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMelanophores --drug effectsen_US
dc.subject.meshRanidaeen_US
dc.subject.meshSkin --cytologyen_US
dc.titleMechanism of histamine induced dispersal response in the isolated web melanophores of a frog, Rana tigerina (Daud.).en_US
dc.typeJournal Articleen_US
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