The Influence of Constant Lighting on The Daily Dynamics of Some Physiological Parameters of Male Wistar Rats
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Date
2020-03
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of Pharmaceutical Research and Allied Sciences
Abstract
The effect of the stay of 6-months-old male Wistar rats under the influence of constant lighting on the dailydynamics of some biochemical parameters was studied. Male Wistar albino rats at the age of 6 months weredivided into 2 groups. The rats from the Group I were housed under a fixed illumination, L:D 14:10 (±180 lux,respectively; 8:00 AM lights on) (unless mentioned otherwise) in a temperature-controlled environment with adlibitum access to tap water and food (rat chow). Animals of Group II were studied under the same experimentalconditions except for the light regime, representing constant light (LL ±180 lux). Both the first and second groupsof animals were kept at the specified light regime for 2 weeks. A number of biochemical parameters of bloodplasma have a reliable daily rhythm, while for other metabolites of an organism a circadian rhythm is not noted.The appearance of the previously absent rhythm of physiological parameters after the application of constantlighting indicates the role of other pacemakers in the metabolism, in addition to illumination. The conductedresearch testifies about the unambiguous modulating influence of constant illumination on the structure of diurnaldynamics of studied biochemical parameters and rectal temperature, and about the initiation of desynchronosisby it
Description
Keywords
photoperiod, desynchronosis, circadian rhythm, rectal temperature, glucose.
Citation
Makartseva Lyudmila, Kozlova Maria, Kucher Sergey, Areshidze David. The Influence of Constant Lighting on The Daily Dynamics of Some Physiological Parameters of Male Wistar Rats. International Journal of Medical Research Professionals. ; : 115-124