Plasma pharmacokinetics of a generic amoxycillin and the innovator brand: a comparison.

Simple item page
dc.contributor.authorGoonetilleke, A Ken_US
dc.contributor.authorMunasingha, J Men_US
dc.contributor.authorGuruge, D Sen_US
dc.contributor.authorSamaraweera, D Sen_US
dc.contributor.authorWeerasena, O Ven_US
dc.date.accessioned2009-05-28T05:15:37Z
dc.date.available2009-05-28T05:15:37Z
dc.date.issued1998-03-13en_US
dc.descriptionThe Ceylon Medical Journal.en_US
dc.description.abstractOBJECTIVE: To compare the bioavailability and plasma pharmacokinetics of a generic brand of amoxycillin (State Pharmaceutical Manufacturing Coporation) selected from the lower price range, with that of the innovation brand (Amoxil, Beecham). DESIGN: Sixteen healthy adult volunteers were allotted to two groups and each group was given a test dose of amoxycillin from each brand. Blood samples were collected at 0, 2, 3 and 4 hours thereafter plasma levels were assayed using high performance liquid chromatography. RESULTS: Analysis of results show that the generic product had similar bioavailability and pharmacokinetics when compared with the innovator product. CONCLUSION: The quality assured generic amoxycillin tested had similar bioavailability as a more costly branded version.en_US
dc.description.affiliationDepartment of Pharmacology, Faculty of Medical Sciences, University of Sri Jayewardenepura.en_US
dc.identifier.citationGoonetilleke AK, Munasingha JM, Guruge DS, Samaraweera DS, Weerasena OV. Plasma pharmacokinetics of a generic amoxycillin and the innovator brand: a comparison. The Ceylon Medical Journal. 1998 Mar; 43(1): 16-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/48191
dc.language.isoengen_US
dc.source.urihttps://www.infolanka.com/CMJhome/en_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAmoxicillin --administration & dosageen_US
dc.subject.meshArea Under Curveen_US
dc.subject.meshBiological Availabilityen_US
dc.subject.meshChromatography, High Pressure Liquiden_US
dc.subject.meshDrugs, Generic --administration & dosageen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPenicillins --administration & dosageen_US
dc.subject.meshReference Valuesen_US
dc.titlePlasma pharmacokinetics of a generic amoxycillin and the innovator brand: a comparison.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Ceylon Medical Journal