Antidepressant activity of hyperforin conjugates of the St. John's wort, Hypericum perforatum Linn.: an experimental study.

Simple item page
dc.contributor.authorMuruganandam, A Ven_US
dc.contributor.authorBhattacharya, S Ken_US
dc.contributor.authorGhosal, Sen_US
dc.date.accessioned2009-05-28T10:40:00Z
dc.date.available2009-05-28T10:40:00Z
dc.date.issued2001-12-23en_US
dc.description.abstractNine extracts of H. perforatum, containing hyperforin in conjugated forms, but devoid of free hyperforin and adhyperforin, were subjected to antidepressant screening using the forced swim test (FST). The observed activity was compared with that of SJW extracts containing hyperforin and adhyperforin (in free form). Results indicate that hyperforin conjugates exhibit significant antidepressant activity as evidenced by the reduced immobility period in the FST in rats.en_US
dc.description.affiliationDepartment of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.en_US
dc.identifier.citationMuruganandam AV, Bhattacharya SK, Ghosal S. Antidepressant activity of hyperforin conjugates of the St. John's wort, Hypericum perforatum Linn.: an experimental study. Indian Journal of Experimental Biology. 2001 Dec; 39(12): 1302-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/55625
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntidepressive Agents --isolation & purificationen_US
dc.subject.meshBicyclo Compoundsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHypericum --chemistryen_US
dc.subject.meshMaleen_US
dc.subject.meshPhloroglucinol --analogs & derivativesen_US
dc.subject.meshPlant Extracts --pharmacologyen_US
dc.subject.meshRatsen_US
dc.subject.meshSwimmingen_US
dc.subject.meshTerpenes --isolation & purificationen_US
dc.titleAntidepressant activity of hyperforin conjugates of the St. John's wort, Hypericum perforatum Linn.: an experimental study.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Experimental Biology