Assessment of abnormal celiac serological marker in newly diagnosed cases of DM-I without gastrointestinal tract symptoms
Loading...
Date
2021-06
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
IJHS Medical Association
Abstract
Objective: To assess the abnormal celiac serological marker (anti-tissue transglutaminase IgA) in newly diagnosed cases of DM-I without gastrointestinal tract symptoms. Material and methods: This cross sectional study was conducted at Department of Pediatric Medicine, Bahawal Victoria Hospital, Bahawalpur. Total 87 newly diagnosed of DM-I without GIT symptoms either male or female having age from 6-16 years were selected for this study. Results: Mean age of the children was 11.43 ± 3.78 years. Out of 70 patients, total 17 (20%) patients found with abnormal celiac serological markers. Total 12 (13.79%) patients were found with family history of DM and abnormal celiac serological marker was seen in 5 (41.67%) patients. Total 75 (86.21%) patients found without family history of DM and abnormal celiac serological marker was seen in 12 (16%) patients. Association between abnormal celiac serological marker and family history of DM was statistically significant with p value 0.05. Conclusion: Results of this study showed a high percentage of abnormal celiac serological marker. Insignificant association of abnormal celiac serological marker with age and gender was detected. But significantly associated with family history of diabetes mellitus.
Description
Keywords
Celiac disease, diabetes mellitus, enteropathy, autoimmune diseases, serological marker
Citation
Khalid Maryam, Jawad Ayesha, Rashid Zahid. Assessment of abnormal celiac serological marker in newly diagnosed cases of DM-I without gastrointestinal tract symptoms. IJHS Medical Association . 2021 Jun; 8(3): 6-9