In vitro evaluation of cytotoxicity of denture adhesives.

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dc.contributor.authorAgarwal, Samarth Kumar
dc.contributor.authorPraveen, G
dc.contributor.authorGupta, Saurabh
dc.contributor.authorTandon, Renu
dc.contributor.authorGupta, Sameer
dc.date.accessioned2012-08-06T07:35:14Z
dc.date.available2012-08-06T07:35:14Z
dc.date.issued2011-07
dc.description.abstractAim: The aim of the study is to assess and compare the cytotoxicity of commercially available four denture adhesives ex-vivo. Materials and Methods: Four commercially available denture adhesives namely Metrodent powder, Fixon powder, Dentiro powder and Fixon cream were selected. Normal saline was used in control group. To evaluate the cytotoxicity of denture adhesives, macrophages were isolated from peritoneal cavity of Swiss albino mice and cell integrity/cell viability method was done by using trypan blue dye. Results: Viable cells were counted and subjected to statistical analysis. ANOVA, F and 't' test were performed, which showed statistically significant values (P < 0.001). The mean percentage of viable cells was highest in the control group (95%) and lowest in Fixon powder (55.66%), with Dentiro powder the mean percentage of viable cells was 63.66%, with Metrodent powder 67.6% while with Fixon cream it was 69.33%. Conclusion: All tested denture adhesives showed varied degree of cytotoxicity that is statistically significant. The degree of toxicity was more in Fixon powder followed by Dentiro powder and Metrodent powder with least in Fixon cream.en_US
dc.identifier.citationAgarwal Samarth Kumar, Praveen G, Gupta Saurabh, Tandon Renu, Gupta Sameer. In vitro evaluation of cytotoxicity of denture adhesives. Indian Journal of Dental Research. 2011 Jul-Aug; 22(4): 526-529.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/140066
dc.language.isoenen_US
dc.source.urihttps://www.ijdr.in/article.asp?issn=0970-9290;year=2011;volume=22;issue=4;spage=526;epage=529;aulast=Agarwalen_US
dc.subjectCell viabilityen_US
dc.subjectcytotoxicityen_US
dc.subjectdenture adhesiveen_US
dc.subjectmacrophagesen_US
dc.subject.meshAdhesives --toxicity
dc.subject.meshAnimals
dc.subject.meshCell Count
dc.subject.meshCell Separation
dc.subject.meshCell Survival --drug effects
dc.subject.meshCells, Cultured
dc.subject.meshColoring Agents --diagnostic use
dc.subject.meshDenture Retention
dc.subject.meshMacrophages, Peritoneal --drug effects
dc.subject.meshMaterials Testing
dc.subject.meshMice
dc.subject.meshTrypan Blue --diagnostic use
dc.titleIn vitro evaluation of cytotoxicity of denture adhesives.en_US
dc.typeArticleen_US
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