DRUG THERAPY OF HYPOPIGMENTARY DISORDERS OF THE SKIN: A HOSPITAL-BASED STUDY

dc.contributor.authorK., GIRISHen_US
dc.contributor.authorGOWDA, NEEPUen_US
dc.contributor.authorR., JYOTHIen_US
dc.contributor.authorARUNNAIR, VIJAYAMATHYen_US
dc.date.accessioned2024-09-24T08:25:06Z
dc.date.available2024-09-24T08:25:06Z
dc.date.issued2023-04
dc.description.abstractObjective: To determine the pattern of drug use, adverse events (AEs), and quality of life (QOL) in hypopigmentary disorders of the skin.Methods: A prospective, observational study was conducted on 48 newly diagnosed and untreated participants with hypopigmentary disorders who attended the dermatology outpatient department (OPD) of a tertiary care hospital in Bangalore, India. The pattern of drug therapy and AEs to the therapy were analyzed using descriptive statistics. The dermatology life quality index (DLQI) score for QOL was assessed before and after treatment using analysis of variance (ANOVA). The participants were monitored every 30 d for three months to study the appropriateness and changes in prescription patterns, AEs, and QOL.Results: Male participants had a mean age of 36.69±15.58, while female participants had a mean age of 40.96±11.88. The different classes of drugs used were calcineurin inhibitors, growth factors, melanizing agents, glucocorticoids (GCs), antifungals, and anti-lepra drugs. QOL improved after treatment. The most common AEs include gastritis (16.6%) and acneiform eruption (10.41%).Conclusion: This study has helped in determining the different patterns of drugs used in hypopigmentary disorders and their positive impact on QOL. The individualized prescribing pattern could improve the clinical and psychosocial outcome of the disease in the future.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Kempegowda Institute of Medical Sciences, Bangaloreen_US
dc.identifier.affiliationsDepartment of Pharmacology, Kempegowda Institute of Medical Sciences, Bangaloreen_US
dc.identifier.affiliationsDepartment of Pharmacology, Kempegowda Institute of Medical Sciences, Bangaloreen_US
dc.identifier.affiliationsDepartment of Pharmacology, KMCH Institute of Health Sciences and Research, Coimbatoreen_US
dc.identifier.citationK. GIRISH, GOWDA NEEPU, R. JYOTHI, ARUNNAIR VIJAYAMATHY . DRUG THERAPY OF HYPOPIGMENTARY DISORDERS OF THE SKIN: A HOSPITAL-BASED STUDY . International Journal of Pharmacy and Pharmaceutical Sciences . 2023 Apr; 15(4): 47-51en_US
dc.identifier.issn0975-1491
dc.identifier.issn2656-0097
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231224
dc.languageenen_US
dc.publisherInnovare Academic Sciences Pvt. Ltd.en_US
dc.relation.issuenumber4en_US
dc.relation.volume15en_US
dc.source.urihttps://doi.org/10.22159/ijpps.2023v15i4.47383en_US
dc.subjectQuality of lifeen_US
dc.subjectTopical therapyen_US
dc.subjectPhototherapyen_US
dc.titleDRUG THERAPY OF HYPOPIGMENTARY DISORDERS OF THE SKIN: A HOSPITAL-BASED STUDYen_US
dc.typeJournal Articleen_US
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