Effect of gamma irradiation on chemical and biological properties of lipopolysaccharide from Salmonella typhimurium.
dc.contributor.author | Naidu, M D | en_US |
dc.contributor.author | Chander, R | en_US |
dc.contributor.author | Nair, P M | en_US |
dc.date.accessioned | 2009-05-28T13:39:41Z | |
dc.date.available | 2009-05-28T13:39:41Z | |
dc.date.issued | 1998-06-10 | en_US |
dc.description.abstract | Lipopolysaccharide (LPS) from S. typhimurium on exposure to gamma-radiation resulted in decrease in toxicity and was less mitogenic, Silver stained profiles of irradiated LPS on polyacrylamide gels revealed complete loss of its heteropolysaccharides which was confirmed further by analysing lipid A and LPS from Salmonella minnesota Re mutants on SDS-PAGE. Glucosamine and 2-keto 3-deoxy-octonate(Kdo) contents were significantly decreased on treatment. Lipid A obtained by removal of heteropolysaccharides from LPS was less toxic on exposure to gamma radiations. | en_US |
dc.description.affiliation | Food Technology Division, Bhabha Atomic Research Centre, Mumbai, India. | en_US |
dc.identifier.citation | Naidu MD, Chander R, Nair PM. Effect of gamma irradiation on chemical and biological properties of lipopolysaccharide from Salmonella typhimurium. Indian Journal of Experimental Biology. 1998 Jun; 36(6): 588-92 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/59701 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.asp | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Gamma Rays | en_US |
dc.subject.mesh | Lipopolysaccharides --chemistry | en_US |
dc.subject.mesh | Mice | en_US |
dc.subject.mesh | Mice, Inbred C57BL | en_US |
dc.subject.mesh | Mitogens --pharmacology | en_US |
dc.subject.mesh | Salmonella typhimurium --chemistry | en_US |
dc.subject.mesh | Spleen --cytology | en_US |
dc.title | Effect of gamma irradiation on chemical and biological properties of lipopolysaccharide from Salmonella typhimurium. | en_US |
dc.type | Journal Article | en_US |
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