Production of paclitaxel by Fusarium solani isolated from Taxus celebica.

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dc.contributor.authorChakravarthi, B V S Ken_US
dc.contributor.authorDas, Prasantaen_US
dc.contributor.authorSurendranath, Kalpanaen_US
dc.contributor.authorKarande, Anjali Aen_US
dc.contributor.authorJayabaskaran, Chelliahen_US
dc.date.accessioned2008-06-07en_US
dc.date.accessioned2009-06-01T14:32:02Z
dc.date.available2008-06-07en_US
dc.date.available2009-06-01T14:32:02Z
dc.date.issued2008-06-07en_US
dc.description.abstractA fungus was isolated from the stem cuttings of Taxus celebica, which produced paclitaxel in liquid-grown cultures. The fungus was identified as Fusarium solani based on colony characteristics, morphology of conidia and the 26S rDNA sequence. Paclitaxel was identified by chromatographic and spectroscopic comparison with authentic paclitaxel and its cytotoxic activity towards Jurkat cells in vitro.en_US
dc.description.affiliationDepartment of Biochemistry, Indian Institute of Science, Bangalore 560 012, India.en_US
dc.identifier.citationChakravarthi BV, Das P, Surendranath K, Karande AA, Jayabaskaran C. Production of paclitaxel by Fusarium solani isolated from Taxus celebica. Journal of Biosciences. 2008 Jun; 33(2): 259-67en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/110894
dc.language.isoengen_US
dc.source.urihttps://www.ias.ac.in/jbiosci/index.htmlen_US
dc.subject.meshBase Sequenceen_US
dc.subject.meshChromatography, High Pressure Liquiden_US
dc.subject.meshDNA, Planten_US
dc.subject.meshFusarium --isolation & purificationen_US
dc.subject.meshHumansen_US
dc.subject.meshJurkat Cellsen_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshPaclitaxel --biosynthesisen_US
dc.subject.meshSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionizationen_US
dc.subject.meshTaxus --microbiologyen_US
dc.titleProduction of paclitaxel by Fusarium solani isolated from Taxus celebica.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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