Antioxidant and antiulcer activity of aqueous extract of a polyherbal formulation.

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dc.contributor.authorShirwaikar, Annieen_US
dc.contributor.authorRam, H N Aswathaen_US
dc.contributor.authorMohapatra, Pen_US
dc.date.accessioned2009-05-28T14:05:25Z
dc.date.available2009-05-28T14:05:25Z
dc.date.issued2006-06-21en_US
dc.description.abstractThe aqueous extract of Hingwashtak churna was evaluated for gastroprotection in rats using the ibuprofen and ethanol induced ulcer models. Efficacy was assessed by determination of mean ulcer size, ulcer number and ulcer index. Oral administration of the aqueous extract (750 mg/kg) significantly protected against gastric lesions by 84.96% and 91.12% as compared to ranititidine (95.54 and 95.2%) in the ibuprofen and alcohol induced ulcer models respectively. The findings suggest that the significant gastroprotective activity could be mediated by its antioxidant activity which was evaluated by using different antioxidant models of screening.en_US
dc.description.affiliationDepartment of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal 576 104, India. annieshirwaikar@yahoo.comen_US
dc.identifier.citationShirwaikar A, Ram HN, Mohapatra P. Antioxidant and antiulcer activity of aqueous extract of a polyherbal formulation. Indian Journal of Experimental Biology. 2006 Jun; 44(6): 474-80en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/60257
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.source.urihttps://nopr.niscair.res.in/bitstream/123456789/6522/1/IJEB%2044%286%29%20474-480.pdfen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAlcohols --metabolismen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnti-Ulcer Agents --pharmacologyen_US
dc.subject.meshAntioxidants --metabolismen_US
dc.subject.meshBenzothiazolesen_US
dc.subject.meshEthanol --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshIbuprofen --pharmacologyen_US
dc.subject.meshLipid Peroxidationen_US
dc.subject.meshMaleen_US
dc.subject.meshNitric Oxide --metabolismen_US
dc.subject.meshPeptic Ulcer --chemically induceden_US
dc.subject.meshPhytotherapy --methodsen_US
dc.subject.meshPlant Extractsen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshSulfonic Acids --chemistryen_US
dc.titleAntioxidant and antiulcer activity of aqueous extract of a polyherbal formulation.en_US
dc.typeJournal Articleen_US
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