Serum - ascites albumin and cholesterol gradients in differential diagnosis of ascites.

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dc.contributor.authorVyakaranam, Sapna
dc.contributor.authorNori, Srinivas
dc.contributor.authorSastry, M Gurumurthy
dc.contributor.authorVyakaranam, Sudhir Bhargav
dc.contributor.authorBhongir, Aparna Varma
dc.date.accessioned2014-06-06T06:02:27Z
dc.date.available2014-06-06T06:02:27Z
dc.date.issued2011-07
dc.description.abstractBackground: Differential diagnosis of ascites is a common clinical problem. Less expensive biochemical techniques are required to differentiate ascites with unknown etiology. Aim: To evaluate the diagnostic efficiency of ascitic fluid cholesterol, serum ascites albumin gradient (SAAG) and serum ascites cholesterol gradients (SACG) in differentiating cirrhotic, tuberculous and malignant ascites. Methods: 50 patients (25 with hepatic cirrhosis, 15 with tuberculosis and10 with malignancy) were evaluated for ascitic fluid total protein, albumin, cholesterol, SAAG and SACG. Results: The mean ascitic fluid cholesterol was significantly higher in malignant ascites when compared with cirrhosis and tuberculous ascites (p= 0.0001 each). The difference between tuberculous and cirrhotic ascites was also significant (p= 0.001). The mean value of SAAG was significantly higher in cirrhosis when compared with tuberculous and malignant ascites (p= 0.0001; p= 0.001 respectively) but the difference between tuberculous and malignant ascites was not significant The mean SACG was significantly lower in malignant compared to tuberculous and cirrhotic ascites (p= 0.0001; p= 0.001 respectively). The difference between tuberculous and cirrhotic ascites was not significant. Conclusion: SAAG is a better marker to differentiate cirrhotic ascites from tuberculous and malignant ascites. Ascitic fluid cholesterol and SACG are better markers to differentiate malignant ascites from cirrhotic and tuberculous ascites.en_US
dc.identifier.citationVyakaranam Sapna, Nori Srinivas, Sastry M Gurumurthy, Vyakaranam Sudhir Bhargav, Bhongir Aparna Varma. Serum - ascites albumin and cholesterol gradients in differential diagnosis of ascites. National Journal of Integrated Research in Medicine. 2011 Jul-Sept; 2(3): 22-28.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/151752
dc.language.isoenen_US
dc.source.urihttps://www.scopemed.org/?mno=10072en_US
dc.subjectCirrhosisen_US
dc.subjectAscitic fluid cholesterolen_US
dc.subjectTuberculous peritonitisen_US
dc.subjectMalignant ascitesen_US
dc.titleSerum - ascites albumin and cholesterol gradients in differential diagnosis of ascites.en_US
dc.typeArticleen_US
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