Impact of anti-tubercular treatment on weight and symptoms of category I tuberculosis patients in an urban city of central India

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dc.contributor.authorBarnwal, Rajan K.en_US
dc.contributor.authorGawande, Avinash V.en_US
dc.contributor.authorNarlawar, Uday W.en_US
dc.contributor.authorZurmure, Sandip A.en_US
dc.date.accessioned2020-05-06T09:52:56Z
dc.date.available2020-05-06T09:52:56Z
dc.date.issued2020-02
dc.description.abstractBackground: Sputum conversion and weight gain are prognostic markers of treatment outcome in tuberculosis (TB) patients. Very few studies in India have assessed impact of TB treatment on weight of patients and perceived improvement in symptoms. This prospective study aimed to assess the impact of anti-tubercular treatment on weight and perceived symptoms.Methods: Three interviews were done for each patient i.e. at start (within 7 days of starting anti-tubercular treatment), at the end of intensive phase and at the end of continuation phase for recording body weight and perceived symptoms. Descriptive statistics were used to summarize baseline characteristics. Mean scores at different stages of treatment were compared by repeat measure ANOVA. P<0.05 was considered to be statistically significant.Results: Out of 58 study subjects enrolled for the study, 53 could be followed up till the end. Mean weight improved in six months of anti-tubercular treatment. Improvement was statistically non-significant. Cough and fever were the most common symptoms prior to beginning of treatment. After the first 2 months the proportion of subjects with symptoms declined for all five symptoms i.e. fever, cough, chest pain, sweats, and dyspnoea.Conclusions: There was positive impact on weight gain in patients under category I treatment. The symptoms improved drastically in first two months with near complete resolution in six months of treatment.en_US
dc.identifier.affiliationsDepartment of Community Medicine, Government Medical College, Nagpur, Maharashtra, Indiaen_US
dc.identifier.citationBarnwal Rajan K., Gawande Avinash V., Narlawar Uday W., Zurmure Sandip A.. Impact of anti-tubercular treatment on weight and symptoms of category I tuberculosis patients in an urban city of central India. International Journal of Community Medicine and Public Health. 2020 Feb; 7(2): 491-494en_US
dc.identifier.issn2394-6032
dc.identifier.issn2394-6040
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/202104
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2394-6040.ijcmph20200051en_US
dc.subjectTuberculosisen_US
dc.subjectSymptomsen_US
dc.subjectWeight gainen_US
dc.subjectCentral Indiaen_US
dc.titleImpact of anti-tubercular treatment on weight and symptoms of category I tuberculosis patients in an urban city of central Indiaen_US
dc.typeJournal Articleen_US
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