Anticarcinogenic effects of an aqueous infusion of cloves on skin carcinogenesis.

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dc.contributor.authorBanerjee, Sarmisthaen_US
dc.contributor.authorDas, Suktaen_US
dc.date.accessioned2009-05-27T17:52:28Z
dc.date.available2009-05-27T17:52:28Z
dc.date.issued2005-07-21en_US
dc.descriptionAsian Pacific Journal of Cancer Prevention.en_US
dc.description.abstractSpices and flavouring agents are now receiving increasing attention as many of them have been shown to have anticarcinogenic properties. Cloves, sun-dried unopened flower buds from the plant Syzygium aromaticum L, are commonly used as a spice and food flavour. The present study was designed to investigate the chemopreventive action of aqueous infusion of cloves on 9,10-dimethyl benz(a)anthracene (DMBA) and croton oil induced skin carcinogenesis in Swiss mice. The results indicate protection against skin papilloma formation in a dose dependent manner. It has been shown that oral administration of aqueous infusions of clove at a dose of 100 microl/mouse/day not only delays the formation of papilloma but also reduces the incidence of papilloma as well as the cumulative number of papillomas per papilloma bearing mouse. Our observations suggest a promising role for cloves in restriction of the carcinogenesis process.en_US
dc.description.affiliationDept. of Cancer Chemoprevention, Chittarajan National Cancer Institute, 37 S.P. Mukherjee Road, Kolkata 700026, West Bengal, India. rmisti@rediffmail.comen_US
dc.identifier.citationBanerjee S, Das S. Anticarcinogenic effects of an aqueous infusion of cloves on skin carcinogenesis. Asian Pacific Journal of Cancer Prevention. 2005 Jul-Sep; 6(3): 304-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/38067
dc.language.isoengen_US
dc.source.urihttps://www.apocp.orgen_US
dc.subject.mesh9,10-Dimethyl-1,2-benzanthraceneen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCarcinogensen_US
dc.subject.meshCell Transformation, Neoplastic --drug effectsen_US
dc.subject.meshChemopreventionen_US
dc.subject.meshEugenia --chemistryen_US
dc.subject.meshMiceen_US
dc.subject.meshNeoplasms, Experimentalen_US
dc.subject.meshPapilloma --physiopathologyen_US
dc.subject.meshPlant Extracts --pharmacologyen_US
dc.subject.meshSkin Neoplasms --physiopathologyen_US
dc.titleAnticarcinogenic effects of an aqueous infusion of cloves on skin carcinogenesis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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